Protective effects of baicalin against deoxynivalenol-induced oxidative and inflammatory damage in chicken-derived hepatic 3D cell cultures
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DOI: 10.1038/s41598-025-95868-0
Abstract: Deoxynivalenol (DON) is a trichothecene mycotoxin often contaminating grains used in poultry feed production and causing several adverse effects in farm animals. Therefore, it is important to investigate compounds that can be potential candidates to… read more here.
Keywords: effects baicalin; chicken derived; hepatic cell; cell cultures ... See more keywords
Elevated nitric oxide levels associated with hepatic cell apoptosis during liver injury
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DOI: 10.1111/hepr.12783
Abstract: Hepatic injury is a major event in liver surgery such as liver transplantation and it always leads to hepatic cell apoptosis. Nitric oxide (NO) is a key signaling regulation molecule. Many researchers have shown that… read more here.
Keywords: hepatic cell; liver; cell apoptosis; injury ... See more keywords
Deconvolution analysis identified altered hepatic cell landscape in primary sclerosing cholangitis and primary biliary cholangitis
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DOI: 10.3389/fmed.2024.1327973
Abstract: Introduction Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are characterized by ductular reaction, hepatic inflammation, and liver fibrosis. Hepatic cells are heterogeneous, and functional roles of different hepatic cell phenotypes are still not… read more here.
Keywords: deconvolution analysis; cholangitis; hepatic cell; signature ... See more keywords
Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death
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DOI: 10.3390/ijms231710148
Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease that urgently needs effective therapy. Rosavin, a major constituent of the Rhodiola Rosea plant of the family Crassulaceae, is believed… read more here.
Keywords: cell death; hepatic cell; via targeting; targeting hepatic ... See more keywords
Mechanistic insights into hepatic cell type-specific contributions to acetaminophen-induced acute liver injury
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DOI: 10.3748/wjg.v31.i45.112720
Abstract: Acetaminophen [N-acetyl-p-aminophenol (APAP)] overdose is a leading cause of acute liver failure worldwide, chiefly due to its hepatotoxic effects. The pathogenesis of APAP-induced acute liver injury (ALI) involves complex interactions among various hepatic cell types,… read more here.
Keywords: mechanistic insights; induced acute; acute liver; hepatic cell ... See more keywords