MS-275 induces hepatic FGF21 expression via H3K18ac-mediated CREBH signal.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-18-0259
Abstract: Fibroblast growth factor 21(FGF21) plays an important role in the regulation of lipid and glucose metabolism. MS-275, as a class I-specific histone deacetylase (HDAC) inhibitor, has also been reported to affect energy metabolism. In this… read more here.
Keywords: hepatic fgf21; expression; h3k18ac; 275 induces ... See more keywords
Hepatic FGF21: Its Emerging Role in Inter-Organ Crosstalk and Cancers
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.76924
Abstract: Fibroblast growth factor (FGF) 21 is one of the FGF members with special endocrine properties. In the last twenty years, it has attracted intense research and development for its physiological functions that respond to dietary… read more here.
Keywords: organ crosstalk; fgf21 emerging; inter organ; hepatic fgf21 ... See more keywords