Proteinuria converts hepatic heparan sulfate to an effective proprotein convertase subtilisin kexin type 9 enzyme binding partner.
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DOI: 10.1016/j.kint.2021.01.023
Abstract: Hepatic uptake of triglyceride-rich remnant lipoproteins is mediated by the low-density lipoprotein receptor, a low-density lipoprotein receptor related protein and the heparan sulfate proteoglycan, syndecan-1. Heparan sulfate proteoglycan also mediates low-density lipoprotein receptor degradation by… read more here.
Keywords: rich remnant; sulfate; triglyceride rich; heparan sulfate ... See more keywords