Galectin‐9: Diverse roles in hepatic immune homeostasis and inflammation
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DOI: 10.1002/hep.29106
Abstract: Glycan‐binding proteins, which include galectins, are involved at all stages of immunity and inflammation, from initiation through resolution. Galectin‐9 (Gal‐9) is highly expressed in the liver and has a wide variety of biological functions in… read more here.
Keywords: homeostasis; galectin diverse; hepatic immune; inflammation ... See more keywords
Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.
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DOI: 10.1097/hep.0000000000000270
Abstract: BACKGROUND AIMS The progression of chronic liver diseases towards liver cirrhosis is accompanied by drastic tissue changes. This study combines elaborate transcriptomic and histological methods aiming at spatially resolving the hepatic immune microenvironment in non-alcoholic… read more here.
Keywords: cell; disease; psc; progression ... See more keywords
Predictive Value of the Hepatic Immune Predictive Index for Patients with Primary Liver Cancer Treated with Immune Checkpoint Inhibitors.
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DOI: 10.1159/000527574
Abstract: BACKGROUND Immune checkpoint inhibitors (ICIs) have improved survival outcomes and resulted in long-term responses in primary liver cancer in some patients. However, its efficacy is limited by the risk of tumor recurrence, resulting in rapid… read more here.
Keywords: liver cancer; hepatic immune; patients primary; immune predictive ... See more keywords