The BMP‐SMAD pathway mediates the impaired hepatic iron metabolism associated with the ERFE‐A260S variant
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25613
Abstract: The erythroferrone (ERFE) is the erythroid regulator of hepatic iron metabolism by suppressing the expression of hepcidin. Congenital dyserythropoietic anemia type II (CDAII) is an inherited hyporegenerative anemia due to biallelic mutations in the SEC23B… read more here.
Keywords: hepatic iron; iron metabolism; erfe a260s; a260s variant ... See more keywords
3D Multiecho Dixon for the Evaluation of Hepatic Iron and Fat in a Clinical Setting
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25630
Abstract: To prospectively evaluate a new 3D‐multiecho‐Dixon (3D‐ME‐Dixon) sequence for the quantification of hepatic iron and fat in a clinical setting. read more here.
Keywords: hepatic iron; clinical setting; iron fat; multiecho dixon ... See more keywords
Automated vessel exclusion technique for quantitative assessment of hepatic iron overload by R2* ‐MRI
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25880
Abstract: Extraction of liver parenchyma is an important step in the evaluation of R2* ‐based hepatic iron content (HIC). Traditionally, this is performed by radiologists via whole‐liver contouring and T2* ‐thresholding to exclude hepatic vessels. However,… read more here.
Keywords: exclusion technique; automated vessel; hepatic iron; vessel exclusion ... See more keywords
MRI‐Based Quantitative R2* Mapping at 3 Tesla Reflects Hepatic Iron Overload and Pathogenesis in Nonalcoholic Fatty Liver Disease Patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27810
Abstract: The role of hepatic iron overload (HIO) in nonalcoholic fatty liver disease (NAFLD) pathogenesis has not been fully elucidated. read more here.
Keywords: iron overload; hepatic iron; liver disease; fatty liver ... See more keywords
Hepatic Iron Quantification Using a Free‐Breathing 3D Radial Gradient Echo Technique and Validation With a 2D Biopsy‐Calibrated R2* Relaxometry Method
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27921
Abstract: Hepatic iron content (HIC) is an important parameter for the management of iron overload. Non‐invasive HIC assessment is often performed using biopsy‐calibrated two‐dimensional breath‐hold Cartesian gradient echo (2D BH GRE) R2*‐MRI. However, breath‐holding is not… read more here.
Keywords: biopsy calibrated; gradient echo; hepatic iron; breathing radial ... See more keywords
Association between thyroid function and assessment of hepatic fat and iron contents by magnetic resonance imaging
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine Connections"
DOI: 10.1530/ec-21-0566
Abstract: The associations of thyroid function parameters with non-alcoholic fatty liver disease (NAFLD) and hepatic iron overload are not entirely clear. We have cross-sectionally investigated these associations among 2734 participants of two population-based cross-sectional studies of… read more here.
Keywords: liver fat; iron contents; iron; hepatic iron ... See more keywords