Long noncoding RNA lncARSR promotes hepatic lipogenesis via Akt/SREBP-1c pathway and contributes to the pathogenesis of nonalcoholic steatohepatitis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.127
Abstract: Non-alcoholic fatty liver disease and steatohepatitis (NAFLD and NASH) account for the majority of liver disease in industrialized countries. However, the pathogenesis still unclear. Long non-coding RNAs (lncRNAs) has been reported to be involved in… read more here.
Keywords: long noncoding; lipogenesis; lncarsr; steatohepatitis ... See more keywords
Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19803-9
Abstract: Hepatic lipogenesis is normally tightly regulated but is aberrantly elevated in obesity. Fibroblast Growth Factor-15/19 (mouse FGF15, human FGF19) are bile acid-induced late fed-state gut hormones that decrease hepatic lipid levels by unclear mechanisms. We… read more here.
Keywords: shp dnmt3a; lipogenesis; fgf15; late fed ... See more keywords
Evaluation of hepatic lipogenesis and antioxidant status of broiler chickens fed mountain celery
Sign Up to like & getrecommendations! Published in 2018 at "BMC Veterinary Research"
DOI: 10.1186/s12917-018-1561-6
Abstract: BackgroundFatness is an unwanted side effect of genetic selection in broiler chickens. In this study, we introduce mountain celery powder as a feed supplement to suppress lipogenesis and improve antioxidant status in broiler chickens. Male… read more here.
Keywords: broiler; mountain celery; lipogenesis; broiler chickens ... See more keywords
Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling
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DOI: 10.1371/journal.pone.0181393
Abstract: Olive oil consumption is beneficial for health as it is associated with a decreased prevalence of cancer and cardiovascular diseases. Oleic acid is, by far, the most abundant component of olive oil. Since it can… read more here.
Keywords: oleic acid; mice; acid; hepatic lipogenesis ... See more keywords
Abelmoschus esculentus subfractions ameliorate hepatic lipogenesis and lipid uptake via regulating dipeptidyl peptidase-4—With improving insulin resistance
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DOI: 10.1371/journal.pone.0265444
Abstract: Nonalcoholic fatty liver disease (NAFLD) is recognized as the liver component of metabolic syndrome. The regulation of hepatic lipid should be emphasized to prevent accompanying illness. As AMP-activated protein kinase (AMPK) and sterol regulatory element… read more here.
Keywords: dipeptidyl peptidase; insulin resistance; hepatic lipogenesis; lipid uptake ... See more keywords