Bidirectional cross talk between uveal melanoma cells and hepatic myofibroblasts promotes inflammation-induced chemokines expression
Sign Up to like & getrecommendations! Published in 2017 at "Acta Ophthalmologica"
DOI: 10.1111/j.1755-3768.2017.01189
Abstract: Purpose Uveal melanoma (UM) is the most common primary ocular neoplasm in adults. Its cause is largely unknown, and no risk factors have yet been identified. The metastatic disease develops in up to 50% of… read more here.
Keywords: uveal melanoma; hepatic microenvironment; expression; inflammation ... See more keywords
Targeting the Hepatic Microenvironment to Improve Ischemia/Reperfusion Injury: New Insights into the Immune and Metabolic Compartments
Sign Up to like & getrecommendations! Published in 2022 at "Aging and Disease"
DOI: 10.14336/ad.2022.0109
Abstract: Hepatic ischemia/reperfusion injury (IRI) is mainly characterized by high activation of immune inflammatory responses and metabolic responses. Understanding the molecular and metabolic mechanisms underlying development of hepatic IRI is critical for developing effective therapies for… read more here.
Keywords: microenvironment; iri; hepatic microenvironment; injury ... See more keywords
Cholangiokines: undervalued modulators in the hepatic microenvironment
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1192840
Abstract: The biliary epithelial cells, also known as cholangiocytes, line the intra- and extrahepatic bile ducts, forming a barrier between intra- and extra-ductal environments. Cholangiocytes are mostly known to modulate bile composition and transportation. In hepatobiliary… read more here.
Keywords: undervalued modulators; modulators hepatic; microenvironment; hepatic microenvironment ... See more keywords
Vascular Heterogeneity With a Special Focus on the Hepatic Microenvironment
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.591901
Abstract: Utilizing single-cell sequencing, recent studies were able to analyze at a greater resolution the heterogeneity of the vasculature and its complex composition in different tissues. Differing subpopulations have been detected, distinguishable only by their transcriptome.… read more here.
Keywords: focus hepatic; heterogeneity; hepatic microenvironment; tissue ... See more keywords