An O‐Glycosylation of Fibronectin Mediates Hepatic Osteodystrophy Through α4β1 Integrin
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DOI: 10.1002/jbmr.2916
Abstract: Patients with cholestatic liver disease experience increased fracture risk. Higher circulating levels of a fibronectin isoform called oncofetal fibronectin (oFN) were detected in a subset of such patients. Administering this isoform to mice suppresses osteoblast… read more here.
Keywords: hepatic osteodystrophy; fibronectin; integrin; glycosylation ... See more keywords