Drug–Drug Interactions in People Living With HIV at Risk of Hepatic and Renal Impairment: Current Status and Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.2025
Abstract: Despite the advancement of antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV), drug–drug interactions (DDIs) remain a relevant clinical issue for people living with HIV receiving ART. Antiretroviral (ARV) drugs can be… read more here.
Keywords: living hiv; people living; renal impairment; drug ... See more keywords
Deuterium body array for the simultaneous measurement of hepatic and renal glucose metabolism and gastric emptying with dynamic 3D deuterium metabolic imaging at 7T.
Sign Up to like & getrecommendations! Published in 2023 at "NMR in biomedicine"
DOI: 10.1002/nbm.4926
Abstract: Deuterium metabolic imaging (DMI) is a novel non-invasive method to assess tissue metabolism and organ (patho)physiology in vivo using deuterated substrates, such as [6,6'-2 H2 ]-glucose. The liver and kidneys play a central role in… read more here.
Keywords: metabolism; renal glucose; deuterium; gastric emptying ... See more keywords
Fucoidan alleviates microcystin-LR-induced hepatic, renal, and cardiac oxidative stress and inflammatory injuries in mice
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-06931-z
Abstract: Fucoidans (FUCs) are sulfated polysaccharides that have a wide range of bioactivities. The current study was designed to evaluate the antioxidant potential of FUC against microcystin-LR (MC-LR)-induced toxicity. Five mice groups ( n = 8) were… read more here.
Keywords: hepatic renal; renal cardiac; microcystin induced; group ... See more keywords
Respiratory, hepatic, renal, and hematological disorders among adolescent females environmentally exposed to pesticides, Menoufia governorate, Egypt
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-18420-3
Abstract: Adolescent females are often environmentally exposed to pesticides by living near agricultural fields, by using pesticides at home, or by having contact with contaminated clothes and pesticide application work tools. This study assessed respiratory, hepatic,… read more here.
Keywords: group; hepatic renal; adolescent females; exposed group ... See more keywords
The molecular mechanism underlining the preventive effect of vitamin D against hepatic and renal acute toxicity through the NrF2/BACH1/HO-1 pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117331
Abstract: AIM Drug-induced liver and kidney injuries are worldwide problems that cause restrictions in the use of drugs. The injury is highly mediated by oxidative stress and inflammation pathways. So, demonstrating the role of the natural… read more here.
Keywords: liver kidney; nrf2 bach1; hepatic renal; toxicity ... See more keywords
The glycine betaine role in neurodegenerative, cardiovascular, hepatic, and renal diseases: Insights into disease and dysfunction networks.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119943
Abstract: Glycine betaine (N, N, N-trimethyl amine) is an osmolyte accumulated in cells that is key for cell volume and turgor regulation, is the principal methyl donor in the methionine cycle and is a DNA and… read more here.
Keywords: hepatic renal; glycine betaine; cardiovascular hepatic; neurodegenerative cardiovascular ... See more keywords
Agmatine alleviates hepatic and renal injury in a rat model of obstructive jaundice
Sign Up to like & getrecommendations! Published in 2020 at "PharmaNutrition"
DOI: 10.1016/j.phanu.2020.100212
Abstract: Abstract Background The cholestatic liver disease could develop in association with a wide range of etiologies. The liver is the most affected organ by cholestasis. It has also been found that the kidney is severely… read more here.
Keywords: cholestasis; hepatic renal; renal injury; agmatine alleviates ... See more keywords
Evaluation of hepatotoxicity and nephrotoxicity induced by fenpyroximate in subchronic-orally exposed Wistar rats
Sign Up to like & getrecommendations! Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2096928
Abstract: Abstract Backgrounds Fenpyroximate (FEN) is an acaricide that inhibits the complex I of the mitochondrial respiratory chain. The aim of this work was to explore the hepatotoxic and nephrotoxic effects of FEN on Wistar rats.… read more here.
Keywords: hepatotoxicity nephrotoxicity; nephrotoxicity induced; wistar; wistar rats ... See more keywords
375. Tolerability of Anidulafungin for Candidemia in Patients With Hepatic or Renal Dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.386
Abstract: Abstract Background Anidulafungin has been prescribed in patients with candidemia, especially hepatic or renal dysfunction because of not undergoing metabolism in the liver and kidney. The purpose of this study was to evaluate the safety… read more here.
Keywords: hepatic renal; renal dysfunction; ast alt; anidulafungin therapy ... See more keywords
G588(P) Transient renal and hepatic dysfunction in severe profound hypothyroidism
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-rcpch.569
Abstract: Introduction Thyroxine plays a significant role in hepatic and renal physiology and thyroid dysfunction can therefore produce a wide range of metabolic disturbances. We report two severe hypothyroid paediatric patients presenting with hepatic and renal… read more here.
Keywords: hypothyroidism; hepatic renal; renal hepatic; dysfunction ... See more keywords
Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/3281670
Abstract: The current study was designed to investigate the beneficial role of diosmin, a biologically active flavonoid, against methotrexate- (MTX-) induced hepatic, renal, and cardiac injuries in mice. Male Swiss albino mice received a single intraperitoneal… read more here.
Keywords: hepatic renal; renal cardiac; diosmin; mtx induced ... See more keywords