AST-120 Treatment Alters the Gut Microbiota Composition and Suppresses Hepatic Triglyceride Levels in Obese Mice
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine Research"
DOI: 10.1080/07435800.2021.1927074
Abstract: ABSTRACT Background: The prevalence of nonalcoholic fatty liver disease (NAFLD) has been increasing worldwide. The existence of a relationship between the microbiota and the pathology of hepatic steatosis is also becoming increasingly clear. AST-120, an… read more here.
Keywords: hepatic triglyceride; triglyceride levels; 120 treatment; gut microbiota ... See more keywords
PRMT5 inhibition induces pro‐inflammatory macrophage polarization and increased hepatic triglyceride levels without affecting atherosclerosis in mice
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17676
Abstract: Protein arginine methyltransferase 5 (PRMT5) controls inflammation and metabolism through modulation of histone methylation and gene transcription. Given the important role of inflammation and metabolism in atherosclerotic cardiovascular disease, here we examined the role of… read more here.
Keywords: increased hepatic; triglyceride levels; atherosclerosis; mice ... See more keywords