Tamoxifen reduces hepatic VLDL production and GH secretion in women: a possible mechanism for steatosis development.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of endocrinology"
DOI: 10.1530/eje-17-0151
Abstract: CONTEXT Growth hormone (GH) stimulates hepatic synthesis of very-low-density lipoproteins (VLDL), whereas hepatic steatosis develops as a result of GH deficiency. Steatosis is also a complication of tamoxifen treatment, the cause of which is not… read more here.
Keywords: secretion; hepatic vldl; vldl; vldl apob ... See more keywords
Long Noncoding RNA lncRHL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db21-1145
Abstract: Dysregulation of hepatic VLDL secretion contributes to the pathogenesis of metabolic diseases, such as nonalcoholic fatty liver disease (NAFLD) and hyperlipidemia. Accumulating evidence has suggested that long noncoding RNAs (lncRNAs) had malfunctioning roles in the… read more here.
Keywords: secretion; bmal1; hepatic vldl; vldl secretion ... See more keywords