Top advances of the year: Hepatobiliary cancers
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DOI: 10.1002/cncr.34652
Abstract: This commentary reviews top advances in hepatobiliary cancer research in 2021–2022, focusing on leveraging immunotherapeutics in combination with other therapies earlier in the disease course and targeted to patient's individualized biomarkers that may predict response… read more here.
Keywords: hepatobiliary cancers; top advances; year hepatobiliary; advances year ... See more keywords
The role of the gut microbiome in the development of hepatobiliary cancers.
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DOI: 10.1097/hep.0000000000000406
Abstract: Hepatobiliary cancers (HBC), including hepatocellular carcinoma (HCC) and cancers of the biliary tract, share high mortality and rising incidence rates. They may also share several risk factors related to unhealthy Western-type dietary and lifestyle patterns… read more here.
Keywords: liver; gut; development; hepatobiliary cancers ... See more keywords
Cell-free DNA copy number variations predict efficacy of immune checkpoint inhibitor-based therapy in hepatobiliary cancers
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DOI: 10.1136/jitc-2020-001942
Abstract: Background This study was designed to screen potential biomarkers in plasma cell-free DNA (cfDNA) for predicting the clinical outcome of immune checkpoint inhibitor (ICI)-based therapy in advanced hepatobiliary cancers. Methods Three cohorts including 187 patients… read more here.
Keywords: inhibitor; ici; cnv risk; hepatobiliary cancers ... See more keywords
Gut microbiome is associated with the clinical response to anti-PD-1 based immunotherapy in hepatobiliary cancers
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DOI: 10.1136/jitc-2021-003334
Abstract: Background The gut microbiome is associated with the response to immunotherapy for different cancers. However, the impact of the gut microbiome on hepatobiliary cancers receiving immunotherapy remains unknown. This study aims to investigate the relationship… read more here.
Keywords: response; group; hepatobiliary cancers; gut microbiome ... See more keywords
Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star
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DOI: 10.1158/1535-7163.mct-21-0363
Abstract: Hepatobiliary cancers are a heterogeneous group of malignancies with a dismal prognosis. Despite intensive research efforts focused on these tumors, methods for early diagnosis and effective targeted therapies are still lacking. Exosomes, released by most… read more here.
Keywords: rnas hepatobiliary; cancer; noncoding rnas; exosomal noncoding ... See more keywords
Significance of serum ferritin as a prognostic factor in advanced hepatobiliary cancer patients treated with Korean medicine: a retrospective cohort study
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DOI: 10.1186/s12906-018-2240-7
Abstract: BackgroundAdvanced hepatobiliary cancers are highly lethal cancers that require precise prediction in clinical practice. Serum ferritin level increases in malignancy and high serum ferritin level is associated with poor survival in various cancers. This study… read more here.
Keywords: medicine; serum ferritin; hepatobiliary cancers; advanced hepatobiliary ... See more keywords
8th Edition of the AJCC Cancer Staging Manual: Pancreas and Hepatobiliary Cancers
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DOI: 10.1245/s10434-017-6025-x
Abstract: The American Joint Committee on Cancer (AJCC) Staging Manual represents the standard for classifying patients with pancreas and hepatobiliary cancers, predicting prognosis, and guiding treatment decisions. For the new 8th edition, the AJCC Hepatobiliary Task… read more here.
Keywords: hepatobiliary cancers; 8th edition; edition; cancer ... See more keywords
Chemotherapy in patients with hepatobiliary cancers and abnormal hepatic function.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of gastrointestinal oncology"
DOI: 10.21037/jgo.2016.09.17
Abstract: Sorafenib and cisplatin plus gemcitabine currently represent first-line treatment standards in advanced hepatocellular carcinoma and biliary cancer, respectively. Conventional cytotoxic agents (monotherapy or combination therapy) have demonstrated activity in the second-line setting or in those… read more here.
Keywords: chemotherapy; patients hepatobiliary; cancers abnormal; chemotherapy patients ... See more keywords
Novel immunotherapy strategies for hepatobiliary cancers.
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DOI: 10.2217/imt-2018-0024
Abstract: Despite recent advancements in therapeutic options for advanced hepatobiliary cancers, there remains an unmet need for innovative systemic treatments. Immunotherapy has shown an ability to provide prolonged clinical benefit, but this benefit remains limited to… read more here.
Keywords: benefit; immunotherapy strategies; novel immunotherapy; hepatobiliary cancers ... See more keywords
Exploring the role of oncolytic viruses in hepatobiliary cancers.
Sign Up to like & getrecommendations! Published in 2018 at "Immunotherapy"
DOI: 10.2217/imt-2018-0048
Abstract: The standard of care for early hepatobiliary cancers (HBC) includes surgical resection. Liver transplantations or locoregional therapies are beneficial in early hepatocellular carcinoma (HCC) under certain circumstances. Systemic treatments have some benefit in advanced HBC,… read more here.
Keywords: role oncolytic; viruses hepatobiliary; hepatobiliary cancers; exploring role ... See more keywords