Indocyanine green is a sensitive adjunct in the identification and surgical management of local and metastatic hepatoblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3982
Abstract: Hepatoblastoma is the most common primary pediatric liver malignancy. Indocyanine green (ICG) has been described as an adjunct to resection in small series. Its utility remains undefined in larger cohorts. read more here.
Keywords: adjunct identification; indocyanine green; sensitive adjunct; green sensitive ... See more keywords
Current trends and prospects of surgical techniques for hepatoblastoma
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.6795
Abstract: Hepatoblastoma, a common extracranial malignant solid tumor in childhood, is often detected at an advanced stage and is difficult to treat surgically. Despite the availability of multiple comprehensive treatments that can be combined with surgery,… read more here.
Keywords: current trends; surgical techniques; tumor; trends prospects ... See more keywords
Global Burden of Hepatoblastoma From 1990 to 2021 and Projection to 2030
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.71163
Abstract: Hepatoblastoma (HB) is the most common primary pediatric hepatocellular carcinoma, and the five‐year survival rate for HB is the lowest among childhood cancers, as 20% of cases are chemotherapy resistant or unresectable. Understanding the global… read more here.
Keywords: hepatoblastoma 1990; global burden; burden hepatoblastoma; hepatoblastoma ... See more keywords
Cytomorphology of hepatoblastoma with histological correlation and role of SALL4 immunocytochemistry in its diagnosis, subtyping, and prognostication
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22231
Abstract: Hepatoblastoma (HB) is the most common malignant pediatric liver tumor, and cytology material is often the only tissue available for evaluation before definitive therapy. Subcategorization of HB based on cytomorphological features thus carries an important… read more here.
Keywords: prognostication; sall4 immunocytochemistry; role; hepatoblastoma ... See more keywords
An Epigenetic Switch Between Differentiation and Proliferation in Hepatoblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2021.08.020
Abstract: CAAT enhancer binding protein a (C/EBPa) is a Cwidely expressed basic leucine zipper transcription factor that plays diverse roles including the regulation of differentiation and cell-cycle progression. Studies in C/ EBPa-null mice and zebrafish have… read more here.
Keywords: gastroenterology; proliferation; human hepatoblastoma; differentiation ... See more keywords
A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-53802-4
Abstract: Cancers evolve not only through the acquisition and clonal transmission of somatic mutations but also by epigenetic mechanisms that modify cell phenotype. Here, we use histology-guided and spatial transcriptomics to characterize hepatoblastoma, a childhood liver… read more here.
Keywords: histology; lineage; hepatoblastoma; cell ... See more keywords
Contemporary management of hepatoblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000618
Abstract: Purpose of review Hepatoblastoma is the most common primary pediatric liver malignancy. The goal of treatment in hepatoblastoma is complete surgical resection. Recently published multinational collaborative studies are better defining risk factors for disease recurrence… read more here.
Keywords: chemotherapy; hepatoblastoma; treatment; resection ... See more keywords
Sustained Remission After Maintenance Irinotecan in Patient With Multiply Relapsed Hepatoblastoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001544
Abstract: Children with recurrent hepatoblastoma have a poor prognosis and limited treatment options. The authors describe a child with metastatic hepatoblastoma who had multiple relapses. He was treated with surgical resection and adjuvant chemotherapy at first… read more here.
Keywords: irinotecan patient; hepatoblastoma; maintenance; maintenance irinotecan ... See more keywords
A Malignant Hepatoblastoma Mimicking a Benign Mesenchymal Hamartoma: Lessons Learned
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002607
Abstract: Differentiating hepatoblastomas from other congenital benign hepatic tumors is key to surgical management. We, herein, present an unusual case of an antenatally diagnosed liver lesion assessed in the neonatal period. Because of its predominantly cystic… read more here.
Keywords: hepatoblastoma mimicking; hepatoblastoma; mesenchymal hamartoma; malignant hepatoblastoma ... See more keywords
Recurrent Scapular Metastasis From Hepatoblastoma Shown on FDG PET/CT and F-DOPA PET/CT.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000001786
Abstract: We report the case of a 4-year-old girl with a biochemical relapse (plasma α-fetoprotein of 57,987.6 μg/L) after hepatoblastoma and extrahepatic metastases removal and adjuvant chemotherapy. Abdominal ultrasound, CT, and MRI failed to determine the… read more here.
Keywords: pet; metastasis hepatoblastoma; fdg pet; hepatoblastoma ... See more keywords
Hypermethylation of CSF3R is a novel cisplatin resistance marker and predictor of response to postoperative chemotherapy in hepatoblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology Research"
DOI: 10.1111/hepr.13479
Abstract: Most hepatoblastoma patients undergo pre/postoperative cisplatin treatment. Approximately 20% patients are cisplatin resistant, and show poor prognosis and high recurrence rates. However, some cisplatin‐sensitive patients show early recurrence. We consider that a small population of… read more here.
Keywords: postoperative chemotherapy; hypermethylation; cisplatin; cisplatin resistance ... See more keywords