Indocyanine green is a sensitive adjunct in the identification and surgical management of local and metastatic hepatoblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3982
Abstract: Hepatoblastoma is the most common primary pediatric liver malignancy. Indocyanine green (ICG) has been described as an adjunct to resection in small series. Its utility remains undefined in larger cohorts. read more here.
Keywords: adjunct identification; indocyanine green; sensitive adjunct; green sensitive ... See more keywords
Cytomorphology of hepatoblastoma with histological correlation and role of SALL4 immunocytochemistry in its diagnosis, subtyping, and prognostication
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22231
Abstract: Hepatoblastoma (HB) is the most common malignant pediatric liver tumor, and cytology material is often the only tissue available for evaluation before definitive therapy. Subcategorization of HB based on cytomorphological features thus carries an important… read more here.
Keywords: prognostication; sall4 immunocytochemistry; role; hepatoblastoma ... See more keywords
An Epigenetic Switch Between Differentiation and Proliferation in Hepatoblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2021.08.020
Abstract: CAAT enhancer binding protein a (C/EBPa) is a Cwidely expressed basic leucine zipper transcription factor that plays diverse roles including the regulation of differentiation and cell-cycle progression. Studies in C/ EBPa-null mice and zebrafish have… read more here.
Keywords: gastroenterology; proliferation; human hepatoblastoma; differentiation ... See more keywords
Contemporary management of hepatoblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000618
Abstract: Purpose of review Hepatoblastoma is the most common primary pediatric liver malignancy. The goal of treatment in hepatoblastoma is complete surgical resection. Recently published multinational collaborative studies are better defining risk factors for disease recurrence… read more here.
Keywords: chemotherapy; hepatoblastoma; treatment; resection ... See more keywords
Sustained Remission After Maintenance Irinotecan in Patient With Multiply Relapsed Hepatoblastoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001544
Abstract: Children with recurrent hepatoblastoma have a poor prognosis and limited treatment options. The authors describe a child with metastatic hepatoblastoma who had multiple relapses. He was treated with surgical resection and adjuvant chemotherapy at first… read more here.
Keywords: irinotecan patient; hepatoblastoma; maintenance; maintenance irinotecan ... See more keywords
A Malignant Hepatoblastoma Mimicking a Benign Mesenchymal Hamartoma: Lessons Learned
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002607
Abstract: Differentiating hepatoblastomas from other congenital benign hepatic tumors is key to surgical management. We, herein, present an unusual case of an antenatally diagnosed liver lesion assessed in the neonatal period. Because of its predominantly cystic… read more here.
Keywords: hepatoblastoma mimicking; hepatoblastoma; mesenchymal hamartoma; malignant hepatoblastoma ... See more keywords
Recurrent Scapular Metastasis From Hepatoblastoma Shown on FDG PET/CT and F-DOPA PET/CT.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000001786
Abstract: We report the case of a 4-year-old girl with a biochemical relapse (plasma α-fetoprotein of 57,987.6 μg/L) after hepatoblastoma and extrahepatic metastases removal and adjuvant chemotherapy. Abdominal ultrasound, CT, and MRI failed to determine the… read more here.
Keywords: pet; metastasis hepatoblastoma; fdg pet; hepatoblastoma ... See more keywords
Hypermethylation of CSF3R is a novel cisplatin resistance marker and predictor of response to postoperative chemotherapy in hepatoblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology Research"
DOI: 10.1111/hepr.13479
Abstract: Most hepatoblastoma patients undergo pre/postoperative cisplatin treatment. Approximately 20% patients are cisplatin resistant, and show poor prognosis and high recurrence rates. However, some cisplatin‐sensitive patients show early recurrence. We consider that a small population of… read more here.
Keywords: postoperative chemotherapy; hypermethylation; cisplatin; cisplatin resistance ... See more keywords
Hepatoblastoma and Wolf–Hirschhorn syndrome: Coincidence or a new feature of a rare disease?
Sign Up to like & getrecommendations! Published in 2017 at "Pediatrics International"
DOI: 10.1111/ped.13345
Abstract: Wolf–Hirschhorn syndrome (WHS) is a chromosomal disorder characterized by multiple congenital anomalies. Deletion of the distal part of chromosome 4 (4p 16.3) is the underlying cause of the disease. Typically patients have a wide nasal… read more here.
Keywords: feature; hirschhorn syndrome; disease; wolf hirschhorn ... See more keywords
Growing teratoma syndrome in mixed hepatoblastoma with teratoid features
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-241197
Abstract: Mixed epithelial mesenchymal (MEM) hepatoblastoma with teratoid features is rare histological variant of hepatoblastoma and described in case reports. Growing teratoma syndrome (GTS) is a rare and often unrecognised phenomenon generally associated with less than… read more here.
Keywords: growing teratoma; hepatoblastoma teratoid; syndrome mixed; teratoid features ... See more keywords
Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular cancer therapeutics"
DOI: 10.1158/1538-7445.am2022-4005
Abstract: Management of hepatoblastoma (HB), the most frequent pediatric liver cancer, is based on surgical resection and perioperative chemotherapy regimens. In this study, we aimed to identify actionable targets in HB and assess the efficacy of… read more here.
Keywords: driver; igf2 overexpression; hepatoblastoma; combination ... See more keywords