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   Articles with "hepatocellular carcinoma" as a keyword



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Barriers to Surveillance for Hepatocellular Carcinoma in a Multicenter Cohort

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.23504

Abstract: Key Points Question What are the factors associated with noncompletion of hepatocellular carcinoma (HCC) surveillance in patients with high risk? Findings In this cohort study including 629 patients with HCC, most patients did not undergo… read more here.

Keywords: hepatocellular carcinoma; carcinoma multicenter; surveillance hepatocellular; cohort ... See more keywords
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Subacute Abdominal Pain in a Patient With Chronic Liver Disease and Hepatocellular Carcinoma.

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recommendations! Published in 2022 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2022.3888

Abstract: A 66-year-old woman with chronic hepatitis B infection and hepatocellular carcinoma presented with moderate radiating epigastric pain with nausea, anorexia, and water brash without emesis. What is your diagnosis? read more here.

Keywords: hepatocellular carcinoma; abdominal pain; subacute abdominal; pain patient ... See more keywords
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Ten-Year Outcomes of Liver Transplant and Downstaging for Hepatocellular Carcinoma.

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recommendations! Published in 2022 at "JAMA surgery"

DOI: 10.1001/jamasurg.2022.2800

Abstract: Importance National guidelines on transplant selection have adopted successful downstaging to within Milan criteria (MC) as a viable option for the treatment of hepatocellular carcinoma (HCC) before liver transplant (LT). Recurrence of HCC after LT… read more here.

Keywords: hepatocellular carcinoma; year; survival; whose disease ... See more keywords
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Management of Hepatocellular Carcinoma: A Review.

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recommendations! Published in 2023 at "JAMA surgery"

DOI: 10.1001/jamasurg.2022.7989

Abstract: Importance Hepatocellular carcinoma (HCC) is the sixth most common malignancy and fourth leading cause of cancer-related death worldwide. Recent advances in systemic and locoregional therapies have led to changes in many guidelines regarding systemic therapy,… read more here.

Keywords: hepatocellular carcinoma; review; disease; association study ... See more keywords
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hnRNPU Functions as a Novel Therapeutic Target of c-Myc in the Progression of Hepatocellular Carcinoma.

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recommendations! Published in 2020 at "FEBS letters"

DOI: 10.1002/1873-3468.13943

Abstract: Hepatocellular carcinoma (HCC) is the most common liver cancer with high mortality. Here, we found that hnRNPU is overexpressed in HCC tissues and is correlated with the poor prognosis of HCC patients. Besides, hnRNPU is… read more here.

Keywords: hepatocellular carcinoma; hnrnpu functions; hcc; target ... See more keywords

Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6‐independent manner

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recommendations! Published in 2017 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12072

Abstract: Palbociclib, a CDK4/6 inhibitor, has recently been approved for hormone receptor‐positive breast cancer patients. The effects of palbociclib as a treatment for other malignancies, including hepatocellular carcinoma (HCC), are of great clinical interest and are… read more here.

Keywords: hepatocellular carcinoma; palbociclib; hcc; pp5 ampk ... See more keywords
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lncRNA‐PDPK2P promotes hepatocellular carcinoma progression through the PDK1/AKT/Caspase 3 pathway

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recommendations! Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12553

Abstract: Hepatocellular carcinoma (HCC) is a malignancy with one of the worst prognoses. Long noncoding RNA (lncRNA) are emerging as an important regulator of gene expression and function, leading to the development of cancer. The aim… read more here.

Keywords: hepatocellular carcinoma; hcc; pdpk2p; lncrna pdpk2p ... See more keywords
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Loss of RDM1 enhances hepatocellular carcinoma progression via p53 and Ras/Raf/ERK pathways

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recommendations! Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12593

Abstract: Hepatocellular carcinoma (HCC), with its ineffective therapeutic options and poor prognosis, represents a global threat. In the present study, we show that RAD52 motif 1 (RDM1), a key regulator of DNA double‐strand break repair and… read more here.

Keywords: hepatocellular carcinoma; loss rdm1; rdm1; p53 ... See more keywords
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Serum small extracellular vesicle‐derived LINC00853 as a novel diagnostic marker for early hepatocellular carcinoma

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recommendations! Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12745

Abstract: This study aimed to identify novel long noncoding RNA (lncRNA) biomarkers for hepatocellular carcinoma (HCC) using publicly available tissue genomic datasets and validate their diagnostic utility for early‐stage HCC. Differentially expressed lncRNAs between 371 HCC… read more here.

Keywords: hepatocellular carcinoma; extracellular vesicle; hcc; derived linc00853 ... See more keywords
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Platelets are recruited to hepatocellular carcinoma tissues in a CX3CL1‐CX3CR1 dependent manner and induce tumour cell apoptosis

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recommendations! Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12783

Abstract: The mechanisms and biological functions of migrating platelets in cancer remain largely unknown. Here, we analyzed platelet infiltration in hepatocellular carcinoma. We detected platelet extravasation in both mouse and human HCC tissues. CX3CL1 directly induced… read more here.

Keywords: hepatocellular carcinoma; hcc; platelet migration; cell apoptosis ... See more keywords
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Human Proteome Microarray identifies autoantibodies to tumor‐associated antigens as serological biomarkers for the diagnosis of hepatocellular carcinoma

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recommendations! Published in 2023 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13371

Abstract: The identification of the high‐efficiency and non‐invasive biomarkers for hepatocellular carcinoma (HCC) detection is urgently needed. This study aims to screen out potential autoantibodies to tumor‐associated antigens (TAAbs) and to assess their diagnostic value for… read more here.

Keywords: hepatocellular carcinoma; proteome microarray; associated antigens; autoantibodies tumor ... See more keywords