Identification of novel N-acetylcysteine derivatives for the treatment of hepatocellular injury.
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DOI: 10.1039/c7md00409e
Abstract: New anti-hepatocellular injury drugs with better curative effects and fewer side effects are urgently needed at present. In this study, a series of novel N-acetylcysteine (NAC) derivatives were designed, synthesized and biologically evaluated for their… read more here.
Keywords: cell; hepatocellular injury; identification novel; anti hepatocellular ... See more keywords
Hepatocellular injury and hematologic cytopenia after high-dose intravenous immunoglobulin administration
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DOI: 10.1080/15563650.2018.1483024
Abstract: [1] Zhang Y, Huo M, Zhou J, et al. PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel. Comput Methods Programs Biomed. 2010;99:306–314. [2] Jones AW. Elimination half-life of acetone in… read more here.
Keywords: high dose; dose intravenous; hepatocellular injury; cytopenia high ... See more keywords
Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats
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DOI: 10.1093/toxsci/kfy200
Abstract: Recently, studies on circulating microRNAs (miRNAs) as potential biomarkers of drug-induced liver injury (DILI) have received increasing attention. It has been demonstrated that miR-122 and miR-192, which are liver enriched, could be potential biomarkers of… read more here.
Keywords: injury; cholestasis steatosis; injury cholestasis; hepatocellular injury ... See more keywords
Mechanisms of Hepatocellular Injury in Hepatitis A
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DOI: 10.3390/v13050861
Abstract: Hepatitis A virus (HAV) infection is a common cause of acute viral hepatitis worldwide. Despite decades of research, the pathogenic mechanisms of hepatitis A remain incompletely understood. As the replication of HAV is noncytopathic in… read more here.
Keywords: hepatitis; mechanisms hepatocellular; hepatocellular injury; hav infection ... See more keywords