Hepatocyte‐derived MASP1‐enriched small extracellular vesicles activate HSCs to promote liver fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32662
Abstract: Background and Aims: Liver fibrosis is a chronic disease characterized by different etiological agents; dysregulated interactions between hepatocytes and HSCs contribute to this disease. β‐arrestin 1 (ARRB1) plays an important role in liver fibrosis; however,… read more here.
Keywords: fibrosis; liver fibrosis; masp1 enriched; hepatocyte derived ... See more keywords
Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression
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DOI: 10.1172/jci.insight.154314
Abstract: Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4 in hepatocytes but not TEK… read more here.
Keywords: hepatocyte derived; dpp4; derived dpp4; progression ... See more keywords
Hepatocyte-derived Microparticles as Novel Biomarkers for the Diagnosis of Deep Venous Thrombosis in Trauma Patients
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DOI: 10.1177/10760296231153400
Abstract: Venous thromboembolism is a common complication following trauma. We investigated the dynamics of plasma microparticles (MPs) levels and explored their potential as biomarkers of deep vein thromboembolism (DVT) after trauma. A total of 775 patients… read more here.
Keywords: hepatocyte derived; trauma; dvt; trauma patients ... See more keywords