Articles with "hepatocyte model" as a keyword



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Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes

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Published in 2017 at "Cell Biology and Toxicology"

DOI: 10.1007/s10565-017-9392-y

Abstract: Drug-induced liver toxicity is a main reason for withdrawals of new drugs in late clinical phases and post-launch of the drugs. Thus, hepatotoxicity screening of drug candidates in pre-clinical stage is important for reducing drug… read more here.

Keywords: derived hepatocytes; drug; hepatotoxicity; stem ... See more keywords