Flow cytometric method for scoring rat liver micronuclei with simultaneous assessments of hepatocyte proliferation
Sign Up to like & getrecommendations! Published in 2018 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22168
Abstract: The current report describes a newly devised method for automatically scoring the incidence of rat hepatocyte micronuclei (MNHEP) via flow cytometry, with concurrent assessments of hepatocyte proliferation—frequency of Ki‐67‐positive nuclei, and the proportion of polyploid… read more here.
Keywords: assessments hepatocyte; microscopy; method; hepatocyte proliferation ... See more keywords
Chorionic gonadotropin stimulates maternal hepatocyte proliferation during pregnancy.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.09.039
Abstract: The liver increases its size during pregnancy to adapt to metabolic demand associated with pregnancy. Our previous study showed that proliferation of maternal hepatocytes are increased during pregnancy in mice and that estradiol (E2) is… read more here.
Keywords: maternal hepatocyte; chorionic gonadotropin; pregnancy; hepatocyte proliferation ... See more keywords
Photobiomodulation with red light‐emitting diodes accelerates hepatocyte proliferation through reactive oxygen species/extracellular signal‐regulated kinase pathway
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology Research"
DOI: 10.1111/hepr.13182
Abstract: Cell‐based transplantation is an alternate method of liver transplantation to delay the onset of end‐stage liver diseases. For successful treatment, cells need to be expended in vitro expeditiously. However, autogenetic hepatocytes as the ideal cell… read more here.
Keywords: red light; hepatocyte proliferation; proliferation; light emitting ... See more keywords
Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation
Sign Up to like & getrecommendations! Published in 2023 at "Science Signaling"
DOI: 10.1126/scisignal.adf6696
Abstract: Organ size is maintained by the controlled proliferation of distinct cell populations. In the mouse liver, hepatocytes in the midlobular zone that are positive for cyclin D1 (CCND1) repopulate the parenchyma at a constant rate… read more here.
Keywords: stellate cells; stellate; hepatic stellate; liver homeostasis ... See more keywords
Overexpression of miR-125a-5p Inhibits Hepatocyte Proliferation through the STAT3 Regulation In Vivo and In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158661
Abstract: microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous studies have proved that miR-125a was related to LR… read more here.
Keywords: mir 125a; stat3; upregulation mir; proliferation stat3 ... See more keywords