Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression
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DOI: 10.1136/gutjnl-2017-315123
Abstract: Objective Alcoholic liver disease (ALD) is a leading cause of death among chronic liver diseases. However, its pathogenesis has not been completely established. MicroRNAs (miRNAs) are key contributors to liver diseases progression. This study investigated… read more here.
Keywords: txnip overexpression; mir 148a; pyroptosis; hepatocytes foxo1 ... See more keywords