TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment.
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DOI: 10.1016/j.celrep.2021.110018
Abstract: Chronic injury to hepatocytes results in inflammation, steatohepatitis, fibrosis, and nonalcoholic fatty liver disease (NAFLD). The tetraspanin TM4SF5 is implicated in fibrosis and cancer. We investigate the role of TM4SF5 in communication between hepatocytes and… read more here.
Keywords: tm4sf5; tm4sf5 dependent; hepatocytes macrophages; dependent crosstalk ... See more keywords