Syringaldehyde Mitigates Cyclophosphamide‐Induced Liver and Kidney Toxicity in Mice by Inhibiting Oxidative Stress, Inflammation, and Apoptosis Through Modulation of the Nrf2/HO‐1/NFκB Pathway
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DOI: 10.1002/jbt.70172
Abstract: Cyclophosphamide (CYC) is one of the most potent antineoplastic drugs; however, hepatonephrotoxicity, observed following its use, remains one of its most severe side effects. Previous studies have reported that syringaldehyde (SYA), a flavonoid compound, exhibits… read more here.
Keywords: nrf2 pathway; hepatonephrotoxicity; oxidative stress; liver kidney ... See more keywords