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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23178
Abstract: Liver disorders are one of the principal reasons for mortality in the world. Isotretinoin is a systemic retinoid that has been approved for therapy of acne vulgaris since 1982. This drug causes complications in the…
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Keywords:
induced isotretinoin;
effects taurine;
isotretinoin rats;
hepatotoxicity ... See more keywords
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Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28464
Abstract: It has been proposed carbon tetrachloride (CCl4) intoxication due to the production of free radicals and serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) overload results hepatotoxicity. Phosphatidylserine (PS) has…
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Keywords:
induced hepatotoxicity;
hepatoprotective effects;
carbon tetrachloride;
hepatotoxicity rats ... See more keywords
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Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05622-6
Abstract: Background/AimsThe proton pump inhibitor lansoprazole (LPZ) is clinically used to reduce gastric acid secretion, but little is known about its possible hepatoprotective effects. This study aimed to investigate the hepatoprotective effects of LPZ and its…
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Keywords:
proton pump;
hepatoprotective effects;
liver injury;
factor ... See more keywords
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Published in 2021 at "Inflammation"
DOI: 10.1007/s10753-021-01479-y
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation in the joints. Although methotrexate (MX) is the first-line treatment, side effects are common. This study aimed to investigate the effects of quercetin (QT) and/or…
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Keywords:
anti inflammatory;
hepatoprotective effects;
effects quercetin;
rheumatoid arthritis ... See more keywords
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Published in 2020 at "Food bioscience"
DOI: 10.1016/j.fbio.2020.100592
Abstract: Abstract Marine food processing by-products are a valuable source of marine phospholipids with different bioactivities. In a previous study, a method for the extraction of squid phospholipids (SPL) from female squid (Ommastrephes bartrami) gonads was…
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Keywords:
fatty liver;
squid gonad;
hepatoprotective effects;
gonad phospholipids ... See more keywords
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Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.12.128
Abstract: Two new polysaccharides, AZP-1a and AZP-1d, with molecular weights of 3.41 × 104 and 4568 Da, respectively, were extracted from Anoectochilus zhejiangensis and purified by column chromatography. Their structural characteristics were systematically explored and results indicated AZP-1a and…
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Keywords:
hepatoprotective effects;
zhejiangensis;
azp azp;
azp ... See more keywords
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Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00215
Abstract: In recent years, piperlongumine (PL) having specific cytotoxicity has attracted considerable attention for anticancer activity. Through structural modification, the active derivative PL 1-3 shows potential anti-inflammatory activity and low cytotoxicity, but its water solubility is…
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Keywords:
albumin nanoparticles;
hepatoprotective effects;
liver injury;
lipopolysaccharide galactosamine ... See more keywords
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Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-02883-8
Abstract: Cassiae Semen (CS), the seeds of Cassia obtusifolia L. and C. tora L, have a long medicinal history in China, with suggestions for it to relieve constipation and exert hepatoprotective effects. However, the underlying mechanisms…
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Keywords:
gut microbiota;
cassiae semen;
hepatoprotective effects;
non alcoholic ... See more keywords
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Published in 2022 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2021.1917496
Abstract: Abstract Flaxseed (FS) and sesame seed (SS) are traditional and functional foods in traditional Indian medicine for treating various disorders. The present study investigated the hepatoprotective effects of bioactive-fatty acids (FAs) from FS and SS…
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Keywords:
sesame seed;
fatty acids;
ccl4 induced;
seed ... See more keywords
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Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2022.2129672
Abstract: This study was conducted to investigate the protective potential of a pharmaceutically formulated capsule of artichoke leaf powder (ArLP) against aflatoxin B1 (AFB1)-induced hepatotoxicity in male albino rats. In the 42-day experiment, rats were divided…
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Keywords:
characterized extract;
afb1 induced;
effects chemically;
chemically characterized ... See more keywords
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Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2029771
Abstract: Abstract Diabetes mellitus is a chronic metabolic disorder that has been increasing drastically around the worldwide. It is important to emphasize that although many drugs are commercially available to treat diabetes, many of them have…
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Keywords:
hypoglycemic hepatoprotective;
vivo silico;
adult zebrafish;
fisetinidol ... See more keywords