Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP-γ-cyclodextrin
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1138686
Abstract: Icariin as a hepatoprotector from Herba epimedii can expand the cardiovascular and cerebral blood vessels, promote hematopoietic functions, enhance the immune system and show anti-liver tumor activities. However, its low solubility (0.02 mg/mL) limits its… read more here.
Keywords: icariin; complexation; complexation cyclodextrin; solubility ... See more keywords
Activity test of fruit and pomegranate seeds (Punica granatum l) as a hepatoprotector against white male Wistar rats
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacy Education"
DOI: 10.46542/pe.2021.212.220224
Abstract: Introduction: White pomegranate (P. granatum) is a species of the Punicaceae which is thought as hepatoprotector based on its antioxidant secondary metabolite compoundst. Aims: The purpose of study was to determine the hepatoprotector activity of… read more here.
Keywords: hepatoprotector; test dose; 200 bodyweight; test ... See more keywords