Carvacrol protects against λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity by modulating oxidative stress, inflammation, apoptosis, endoplasmic reticulum stress, and autophagy.
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DOI: 10.1002/tox.23784
Abstract: λ-Cyhalothrin, a type II synthetic pyrethroid, has been widely used in households, agriculture, public health, and gardening to control insect pests. Despite its widespread usage, it is known to induce a variety of adverse effects,… read more here.
Keywords: carvacrol; stress; hepatotoxicity nephrotoxicity; oxidative stress ... See more keywords
Protective effect of rutin and β-cyclodextrin against hepatotoxicity and nephrotoxicity induced by lambda-cyhalothrin in Wistar rats: biochemical, pathological indices and molecular analysis
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DOI: 10.1080/1354750x.2022.2087003
Abstract: Abstract Background This study aimed to assess hepatotoxicity and nephrotoxicity of Lambda-cyhalothrin (LCT) and the protective effect of rutin alone and in combination with β-cyclodextrin (β–CD). Materials and methods Male Wistar rats were divided into… read more here.
Keywords: lambda cyhalothrin; hepatotoxicity nephrotoxicity; lct; protective effect ... See more keywords
Evaluation of hepatotoxicity and nephrotoxicity induced by fenpyroximate in subchronic-orally exposed Wistar rats
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DOI: 10.1080/1354750x.2022.2096928
Abstract: Abstract Backgrounds Fenpyroximate (FEN) is an acaricide that inhibits the complex I of the mitochondrial respiratory chain. The aim of this work was to explore the hepatotoxic and nephrotoxic effects of FEN on Wistar rats.… read more here.
Keywords: hepatotoxicity nephrotoxicity; nephrotoxicity induced; wistar; wistar rats ... See more keywords
Fermented Whey modulated AFB1 and OTA-induced hepatotoxicity and nephrotoxicity in vivo. A relative and absolute quantification about sex differences.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicology mechanisms and methods"
DOI: 10.1080/15376516.2023.2195488
Abstract: Aflatoxin B1 (AFB1) and ochratoxin A (OTA) are well-known to promote hepatotoxicity and nephrotoxicity in vivo, which may be counteracted by natural compounds like fermented whey (FW). Carbamoyl phosphate synthetase 1 (CPS1) and kidney injury… read more here.
Keywords: afb1; afb1 ota; nephrotoxicity vivo; hepatotoxicity nephrotoxicity ... See more keywords
Assessment of Ginger Extract and Ginger Nanoparticles Protective Activity against Acetaminophen-Induced Hepatotoxicity and Nephrotoxicity in Rats
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DOI: 10.29261/pakvetj/2019.060
Abstract: Received: Revised: Accepted: Published online: November 28, 2018 March 30, 2019 April 06, 2019 April 23, 2019 Acetaminophen is widely used analgesics all over the world. However, hepatotoxicity and nephrotoxicity are the most features of… read more here.
Keywords: hepatotoxicity nephrotoxicity; ginger; ginger extract; ginger nanoparticles ... See more keywords
Case report: Hepatotoxicity and nephrotoxicity induced by methotrexate in a paediatric patient, what is the role of precision medicine in 2023?
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1130548
Abstract: Methotrexate is an immunosuppressant and chemotherapeutic agent used in the treatment of a range of autoimmune disorders and cancers. Its main serious adverse effects, bone marrow suppression and gastrointestinal complications, arise from its antimetabolite effect.… read more here.
Keywords: hepatotoxicity nephrotoxicity; methotrexate; precision medicine; hepatotoxicity ... See more keywords