Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-017-1551-3
Abstract: Expression of the hepatic peptide hormone hepcidin responds to iron levels via BMP/SMAD signaling, to inflammatory cues via JAK/STAT signaling, to the nutrient-sensing mTOR pathway, as well as to proliferative signals and gluconeogenesis. Here, we… read more here.
Keywords: citrate; metabolism; hormone hepcidin; expression ... See more keywords
Hepcidin and other indicators of iron status, by alpha-1 acid glycoprotein levels, in a cohort of Mexican infants
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Hematology"
DOI: 10.1007/s00277-021-04402-5
Abstract: The purpose of this study was to describe the changes in iron status indicators at 6 and 12 months of age, controlling by inflammation by measuring alpha-1 acid glycoprotein (AGP). This longitudinal study included 48… read more here.
Keywords: iron status; stfr; inflammation; ferritin ... See more keywords
Hepcidin response to three consecutive days of endurance training in hypoxia.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of applied physiology"
DOI: 10.1007/s00421-021-04599-3
Abstract: PURPOSE The purpose of this study was to determine the effects of 3 consecutive days of endurance training in hypoxia on hepcidin responses. METHOD Nine active healthy males completed two trials, consisting of 3 consecutive… read more here.
Keywords: consecutive days; endurance training; training hypoxia; hepcidin ... See more keywords
Hepcidin in Kawasaki disease: upregulation by acute inflammation in patients having resistance to intravenous immunoglobulin therapy
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05822-4
Abstract: Hepcidin is an iron metabolism inhibitor that increases with chronic inflammation. However, it is unclear whether hepcidin indicates acute inflammatory response in Kawasaki disease (KD), which is an acute systemic vasculitis. In this study, we… read more here.
Keywords: hepcidin levels; inflammation; non responders; kawasaki disease ... See more keywords
Importance of Hepcidin in the Etiopathogenesis of Anemia in Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06652-1
Abstract: Anemia is the most common extraintestinal systemic complication of inflammatory bowel disease. Iron deficiency anemia and anemia of chronic disease are among the most frequent types. Intestinal iron absorption is controlled by the activity of… read more here.
Keywords: anemia; inflammatory bowel; disease; hepcidin ... See more keywords
In-depth review: is hepcidin a marker for the heart and the kidney?
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04168-4
Abstract: Iron is an essential trace element involved in oxidation-reduction reactions, oxygen transport and storage, and energy metabolism. Iron in excess can be toxic for cells, since iron produces reactive oxygen species and is important for… read more here.
Keywords: hepcidin marker; hepcidin; depth review; iron ... See more keywords
Impact of serum hepcidin and inflammatory markers on resistance to erythropoiesis-stimulating therapy in haemodialysis patients
Sign Up to like & getrecommendations! Published in 2018 at "International Urology and Nephrology"
DOI: 10.1007/s11255-018-2062-z
Abstract: PurposeAnaemia and resistance to erythropoiesis-stimulating agents (ESAs) are common complications in haemodialysis (HD) patients. We investigated the role of hepcidin in the development of anaemia and ESA resistance/hyporesponsiveness and its relation to the plasma levels… read more here.
Keywords: erythropoiesis stimulating; hscrp; resistance; hepcidin ... See more keywords
Mudskipper (Boleophthalmus pectinirostris) Hepcidin-1 and Hepcidin-2 Present Different Gene Expression Profile and Antibacterial Activity and Possess Distinct Protective Effect against Edwardsiella tarda Infection
Sign Up to like & getrecommendations! Published in 2017 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-017-9352-0
Abstract: Hepcidins are small cysteine-rich antimicrobial peptides that play an important role in fish immunity against pathogens. Most fish species have two or more hepcidin homologs that have distinct functions. This study investigated the immune functions… read more here.
Keywords: bphep bphep; infection; bphep; antibacterial activity ... See more keywords
Identification and characterization of hepcidin from Nile Tilapia (Oreochromis niloticus) in response to bacterial infection and iron overload
Sign Up to like & getrecommendations! Published in 2022 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.737317
Abstract: Abstract Hepcidin (Hepc), as an antimicrobial peptide, plays a vital role in regulating the iron homeostasis and participating in innate immunity. In this study, the open reading frame of Nile tilapia (Oreochromis niloticus) hepcidin mRNA… read more here.
Keywords: expression; bacterial infection; hepcidin; nile tilapia ... See more keywords
Retinoic acid modulates iron metabolism imbalance in anemia of inflammation induced by LPS via reversely regulating hepcidin and ferroportin expression.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.11.022
Abstract: The present study was designed to investigate the effect of retinoic acid (RA) on anemia of inflammation (AI) induced by lipopolysaccharide (LPS) and explore the potential mechanisms. BALB/c mice were randomly assigned into four groups:… read more here.
Keywords: anemia; inflammation; induced lps; expression ... See more keywords
Pentosan Polysulfate to control hepcidin expression in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.113867
Abstract: Hepcidin peptide is crucial in the regulation of systemic iron availability controlling its uptake from the diet and its release from the body storage tissues. Hepcidin dysregulation causes different human disorders ranging from iron overload… read more here.
Keywords: vitro vivo; control hepcidin; hepcidin; iron ... See more keywords