Role of hepcidinâferroportin axis in the pathophysiology, diagnosis, and treatment of anemia of chronic inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Hemodialysis International"
DOI: 10.1111/hdi.12543
Abstract: Anemia of chronic inflammation (ACI) is a frequently diagnosed anemia and portends an independently increased morbidity and poor outcome associated with multiple underlying diseases. The pathophysiology of ACI is multifactorial, resulting from the effects of… read more here.
Keywords: role hepcidin; hepcidin ferroportin; inflammation; chronic inflammation ... See more keywords
Role of the hepcidin-ferroportin axis in pathogen-mediated intracellular iron sequestration in human phagocytic cells.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2017015255
Abstract: Upon infection, pathogen and host compete for the same iron pool, because this trace metal is a crucial micronutrient for all living cells. Iron dysregulation in the host is strongly associated with poor outcomes in… read more here.
Keywords: iron; hepcidin ferroportin; iron sequestration; intracellular iron ... See more keywords