AMPK is not required for the effect of metformin on the inhibition of BMP6-induced hepcidin gene expression in hepatocytes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12976-2
Abstract: The biguanide metformin is used for its antidiabetic effect for many years but how metformin acts remains poorly understood and controversial. AMP-activated protein kinase (AMPK), a protein kinase that plays a key role in maintaining… read more here.
Keywords: metformin; hepcidin gene; induced hepcidin; expression ... See more keywords
Comparison of the effects of zinc oxide and zinc oxide nanoparticles on the expression of hepcidin gene in rat liver
Sign Up to like & getrecommendations! Published in 2020 at "Hormone Molecular Biology and Clinical Investigation"
DOI: 10.1515/hmbci-2020-0038
Abstract: Abstract Objectives Nanoparticles have special properties, such as increased intestinal absorption, permeability, and so on. Zinc oxide (ZnO) nanoparticles have medical applications such as using in drug production. Studies of ZnO nanoparticles have shown the… read more here.
Keywords: hepcidin gene; zno nanoparticles; expression hepcidin; zinc oxide ... See more keywords
Epigallocatechin-3-Gallate (EGCG)-Inducible SMILE Inhibits STAT3-Mediated Hepcidin Gene Expression
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DOI: 10.3390/antiox9060514
Abstract: Hepatic peptide hormone hepcidin, a key regulator of iron metabolism, is induced by inflammatory cytokine interleukin-6 (IL-6) in the pathogenesis of anemia of inflammation or microbial infections. Small heterodimer partner-interacting leucine zipper protein (SMILE)/CREBZF is… read more here.
Keywords: mediated hepcidin; epigallocatechin gallate; hepcidin gene; expression ... See more keywords