Regulation of hepcidin/iron-signalling pathway interactions by commensal bifidobateria plays an important role for the inhibition of metaflammation-related biomarkers.
Sign Up to like & getrecommendations! Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2019.11.009
Abstract: Increased concentration of ferrous iron in the gastrointestinal tract increases the number of various pathogens and induces inflammation. LPS and/or high-fat diet-associated metaflammation is mediated through a quaternary receptor signaling complex containing iron-regulated pathway, IL-6/STAT… read more here.
Keywords: metaflammation; inhibition; lps oleate; hepcidin iron ... See more keywords
Hepcidin and Iron in Health and Disease
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DOI: 10.1146/annurev-med-043021-032816
Abstract: Hepcidin, the iron-regulatory hormone, determines plasma iron concentrations and total body iron content. Hepcidin, secreted by hepatocytes, functions by controlling the activity of the cellular iron exporter ferroportin, which delivers iron to plasma from intestinal… read more here.
Keywords: iron health; iron; hepcidin iron; health disease ... See more keywords