Neo-clerodane diterpenoids from Scutellaria barbata and their reversal multidrug resistance activity in HepG2/Adr cells
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DOI: 10.1016/j.phytol.2019.11.014
Abstract: Abstract Bioassay-guided isolation of the aerial part of Scutellaria barbata (Labiatae) yielded six new neo-clerodane diterpenoids scutegxbatines A–F (1-6), together with thirteen known analogues (7-20). Their structures were elucidated on the basis of extensive spectroscopic… read more here.
Keywords: clerodane diterpenoids; hepg2 adr; neo clerodane; adr cells ... See more keywords
Reverse Multidrug Resistance in Human HepG2/ADR by Anti-miR-21 Combined with Hyperthermia Mediated by Functionalized Gold Nanocages.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00046
Abstract: Multidrug resistance (MDR) remains a formidable challenge to effective clinical cancer therapy. Herein, a nonviral gene delivery system HA/anti-miR-21/PPAuNCs to overcome MDR was reported. This system could condense the microRNA-21 inhibitor (anti-miR-21) into hyaluronic acid-conjugated… read more here.
Keywords: hepg2 adr; anti mir; mir; multidrug resistance ... See more keywords