Identification of the differential and synergic lipotoxic patterns of oleic acid, palmitic acid, and their mixture in 3D HepG2/C3A tissue using liver-on-chip technology.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology progress"
DOI: 10.1002/btpr.70075
Abstract: The metabolic dysfunction-associated steatotic liver disease (MASLD, previously formerly known as non-alcoholic fatty liver disease, NAFLD) is rapidly expanding worldwide in parrallel with the obesity pandemic. Dietary fatty acids including oleic (OA) and palmitic acids… read more here.
Keywords: hepg2 c3a; chip technology; hepg2;
Cytogenotoxicity assessment of 3‐(3,4‐dihydroxyphenyl)‐7,8‐dihydroxycoumarin on HepG2/C3A cells and leukocytes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4384
Abstract: 3‐(3,4‐Dihydroxyphenyl)‐7,8‐dihydroxycoumarin is a newly synthesized coumarin derivative with a potent antioxidant effect. The aim of the present study is to investigate the safety of this compound, determining the in vitro cytotoxic and genotoxic in human… read more here.
Keywords: c3a cells; dihydroxyphenyl dihydroxycoumarin; hepg2 c3a;
Risk assessment of 2β,3β‐19α‐trihydroxyursolic acid from Rubus imperialis (Rosaceae) in HepG2/C3A cells via genotoxicity, metabolism, and cell growth
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4684
Abstract: Rubus imperialis (Rosaceae) is a Brazilian medicinal plant that already exhibited therapeutical perspectives. However, previous studies revealed cellular and/or genetic toxicity of extracts from aerial parts of this plant, as well as other species of… read more here.
Keywords: hepg2 c3a; cell; rubus imperialis; imperialis rosaceae ... See more keywords
A SERS-Active Electrospun Polymer Mesh for Spatially Localized pH Measurements of the Cellular Microenvironment.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02530
Abstract: Extracellular pH (pHe) is an important chemical factor in many cellular processes and disease pathologies. The routine sampling of pHe in vitro could lead to innovative advances in therapeutics. To this end, we have fabricated… read more here.
Keywords: polymer mesh; microenvironment; phe; hepg2 c3a ... See more keywords
Synthesis, Characterization, Antiproliferative Activity of Galloyl Derivatives and Investigation of Cytotoxic Properties in HepG2/C3A cells.
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DOI: 10.2174/1389201023666211217150837
Abstract: BACKGROUND Appropriate substituents in the galloyl group could lead to significant biological properties. OBJECTIVE Novel galloyl-substituted compounds bearing 2-substituted-1,3,4-oxadiazol-5-yl, 5-substituted-1,2,4-triazol-3-yl, and carboxamide groups were synthesized and evaluated for their antiproliferative activity. Additionally, galloyl hydrazide (2)… read more here.
Keywords: c3a cells; antiproliferative activity; galloyl; cell ... See more keywords
Combined cytotoxicity of aflatoxin B1 and deoxynivalenol to hepatoma HepG2/C3A cells
Sign Up to like & getrecommendations! Published in 2017 at "World Mycotoxin Journal"
DOI: 10.3920/wmj2017.2212
Abstract: Co-occurrence of aflatoxin B1 (AFB1) and deoxynivalenol (DON) is one of the most common mycotoxin contaminations in cereal crops and food ingredients. However, the mechanism of their combined toxicity is poorly understood. In the current… read more here.
Keywords: afb1; hepatoma hepg2; combined cytotoxicity; cytotoxicity ... See more keywords