Articles with "hepg2 hep3b" as a keyword



PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0234708

Abstract: Fibroblast growth factor receptors (FGFRs) are frequently altered in a variety of human cancer cells and are overexpressed in hepatocellular carcinoma (HCC). Several literatures have proven that they are efficacious for HCC therapy, however, the… read more here.

Keywords: hcc; hep3b; cul3; hep3b cells ... See more keywords
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STAT3 regulates glycolysis via targeting hexokinase 2 in hepatocellular carcinoma cells

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.15801

Abstract: Signal transducer and activator of transcription 3 (STAT3) and hexokinase 2 (HK2) are involved in hepatocellular carcinoma (HCC). Deregulation of cellular energetics involving an increase in glycolysis is a characteristic of HCC. This study examined… read more here.

Keywords: hcc; glycolysis; stat3; hep3b cells ... See more keywords

In Vitro Cell Density Determines the Sensitivity of Hepatocarcinoma Cells to Ascorbate

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.843742

Abstract: Hepatocellular carcinoma (HCC) is the primary histological subtype of liver cancer, and its incidence rates increase with age. Recently, systemic therapies, such as immune checkpoint inhibitors, monoclonal antibodies, and tyrosine kinase inhibitors (TKIs), have been… read more here.

Keywords: lenvatinib regorafenib; hcc; cell density; hepg2 hep3b ... See more keywords
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MicroRNA-133b Inhibits Proliferation, Cellular Migration, and Invasion via Targeting LASP1 in Hepatocarcinoma Cells.

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Published in 2017 at "Oncology research"

DOI: 10.3727/096504017x14850151453092

Abstract: MicroRNAs (miRs), a class of small noncoding RNAs, are key gene regulators through inducing translational repression or degradation of their target genes. However, the regulatory mechanism of miR-133b underlying hepatocellular carcinoma (HCC) growth and metastasis… read more here.

Keywords: mir 133b; hcc; hepg2 hep3b; proliferation ... See more keywords