Artemyrianolides A-S, Cytotoxic Sesquiterpenoids from Artemisia myriantha.
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DOI: 10.1021/acs.jnatprod.0c00396
Abstract: Random screening suggested that the EtOH extract of Artemisia myriantha (Asteraceae) and its EtOAc fraction had cytotoxicity against HepG2 cells with inhibitory ratios of 30.6% and 53.5% at 50.0 μg/mL. Bioassay-guided isolation of the most… read more here.
Keywords: artemisia myriantha; sesquiterpenoids artemisia; cytotoxic sesquiterpenoids; myriantha ... See more keywords
Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells
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DOI: 10.1093/gastro/goaa049
Abstract: Abstract Background The epithelial-to-mesenchymal transition (EMT) status is associated with programmed death-1 ligand 1 (PD-L1) expression in various cancers. However, the role and molecular mechanism of PD-L1 in the EMT of sorafenib-resistant hepatocellular carcinoma (HCC)… read more here.
Keywords: hcc; sorafenib resistant; hepg2 huh7; huh7 cells ... See more keywords