The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.6b00850
Abstract: Heptosyltransferase I (HepI) catalyzes the addition of l-glycero-β-d-manno-heptose to Kdo2-Lipid A, as part of the biosynthesis of the core region of lipopolysaccharide (LPS). Gram-negative bacteria with gene knockouts of HepI have reduced virulence and enhanced… read more here.
Keywords: protein dynamics; tryptophans tell; adp heptose; stories tryptophans ... See more keywords
Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between Substrate and Positively Charged Residues.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b01005
Abstract: Gram-negative bacterial viability is greatly reduced by the disruption of heptose sugar addition during the biosynthesis of lipopolysaccharide (LPS), an important bacterial outer membrane component. Heptosyltransferase I (HepI), a member of the GT-B structural subclass… read more here.
Keywords: interactions substrate; attract escherichia; positively charged; heptosyltransferase ... See more keywords