Type III-A CRISPR-associated protein Csm6 degrades cyclic hexa-adenylate activator using both CARF and HEPN domains
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DOI: 10.1093/nar/gkaa634
Abstract: Abstract The type III CRISPR–Cas systems provide immunity against invading nucleic acids through the coordinated transcription-dependent DNA targeting and cyclic adenylate (cAn)-activated RNA degradation. Here, we show that both these pathways contribute to the Streptococcus… read more here.
Keywords: hepn domains; hepn; carf hepn; iii crispr ... See more keywords