Articles with "her2 alterations" as a keyword



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Therapeutic strategies for afatinib‐resistant lung cancer harboring HER2 alterations

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Published in 2018 at "Cancer Science"

DOI: 10.1111/cas.13571

Abstract: Human epidermal growth factor receptor 2 (HER2) plays an important role in the pathogenesis of various cancers. HER2 alterations have been suggested to be a therapeutic target in non‐small‐cell lung cancer (NSCLC), just as in… read more here.

Keywords: afatinib; resistance; her2 alterations; cancer ... See more keywords
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HER2 in Non-Small Cell Lung Cancer: A Review of Emerging Therapies

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14174155

Abstract: Simple Summary There are growing data on targeting HER2 alterations, which include gene mutations, gene amplifications, and protein overexpression, for non-small cell lung cancer (NSCLC). Currently, there are limited targeted therapies approved for NSCLC patients… read more here.

Keywords: her2 alterations; lung cancer; non small; her2 ... See more keywords
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Deciphering the Impact of HER2 Alterations on Non-Small-Cell Lung Cancer: From Biological Mechanisms to Therapeutic Approaches

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Published in 2022 at "Journal of Personalized Medicine"

DOI: 10.3390/jpm12101651

Abstract: Despite the recent increase in the number of types of treatments, non-small-cell lung cancer (NSCLC) remains the major cause of death from cancer worldwide. So, there is an urgent need to develop new therapeutic strategies.… read more here.

Keywords: her2 alterations; lung cancer; non small; small cell ... See more keywords