HER2 in Colorectal Carcinoma: Are We There yet?
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DOI: 10.1016/j.path.2020.05.007
Abstract: HER2 (ERBB2) is a member of the ERBB family of receptor tyrosine kinases and functions to drive signaling in the RAS/RAF/MEK/ERK and PI3K/AKT/mTOR pathways. Overall, approximately 2-3% of CRCs exhibit ERBB2 amplification. Multiple phase II… read more here.
Keywords: her2 colorectal; targeted therapy; colorectal carcinoma; carcinoma yet ... See more keywords