The past, present, and future of HER2 (ERBB2) in cancer: Approaches to molecular testing and an evolving role in targeted therapy
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22124
Abstract: Jaclyn F. Hechtman is an assistant member of pathology at Memorial Sloan Kettering Cancer Center in New York City. She practices molecular and gastrointestinal pathology and also participates in assay validation for targetable molecular alterations… read more here.
Keywords: pathology; her2 erbb2; future her2; cancer ... See more keywords
Targeted next‐generation sequencing enables reliable detection of HER2 (ERBB2) status in breast cancer and provides ancillary information of clinical relevance
Sign Up to like & getrecommendations! Published in 2017 at "Genes"
DOI: 10.1002/gcc.22431
Abstract: HER2‐positive breast cancers are a heterogeneous group of tumors, which share amplification and overexpression of HER2. In routine diagnostics, the HER2 (ERBB2) status is currently assessed by immunohistochemistry (IHC) and in situ hybridization (ISH). Data… read more here.
Keywords: status; targeted next; erbb2 status; breast ... See more keywords
CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-0707
Abstract: Expression of the ectonucleotidase CD73 by tumor cells, stromal cells, and immune cells is associated in cancer with immune suppression. In this study, we investigated the role of CD73 on the activity of the anti-HER2/ErbB2… read more here.
Keywords: antibody; her2 erbb2; cd73; expression ... See more keywords
Acral lentiginous melanoma with HER2/ErbB2 amplification
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2021.4115
Abstract: EJD, vol. 31, n◦ 4, July-August 2021 suggests that retrograde spread of the virus from a primary nipple condyloma is possible. The spread may also be due to leakage of HPV to the blood circulation… read more here.
Keywords: melanoma her2; dermatology; lentiginous melanoma; her2 erbb2 ... See more keywords