The Effects of Pertuzumab and Its Combination with Trastuzumab on HER2 Homodimerization and Phosphorylation
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DOI: 10.3390/cancers11030375
Abstract: Pertuzumab (Perjeta) is an anti-HER2 monoclonal antibody that is used for treatment of HER2-positive breast cancers in combination with trastuzumab (Herceptin) and docetaxel and showed promising clinical outcomes. Pertuzumab is suggested to block heterodimerization of… read more here.
Keywords: pertuzumab; her2 homodimerization; trastuzumab; her2 ... See more keywords