HER2 mutation as an emerging target in advanced breast cancer
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Science"
DOI: 10.1111/cas.16148
Abstract: HER2 activating mutations have emerged as oncogenic drivers and therapeutic targets in a variety of human tumors. In breast cancer, these deregulations occur at low frequency, and are mostly detected in HER2‐nonamplified, metastatic disease. Preclinical… read more here.
Keywords: her2 mutation; her2; cancer; breast cancer ... See more keywords
CT texture features of lung adenocarcinoma with HER2 mutation
Sign Up to like & getrecommendations! Published in 2025 at "BMC Cancer"
DOI: 10.1186/s12885-025-13686-z
Abstract: Mutations in human receptor tyrosine kinase epidermal growth factor receptor-2 (HER2) are rare. This study aimed to investigate the clinical characteristics and computed tomography (CT) texture features of lung adenocarcinoma (LUAD) patients with HER2 mutation.… read more here.
Keywords: her2; luad patients; her2 mutation; luad her2 ... See more keywords
HER2 mutations in pulmonary adenocarcinoma presenting with ground-glass nodules
Sign Up to like & getrecommendations! Published in 2025 at "World Journal of Surgical Oncology"
DOI: 10.1186/s12957-025-03955-3
Abstract: Human epidermal growth factor receptor 2 (HER2) mutations have been identified as oncogenic drivers and therapeutic targets in Non-small cell lung cancers (NSCLCs). The role of HER2 mutation in lung adenocarcinoma presented as sub-solid nodules… read more here.
Keywords: age; adenocarcinoma; her2 mutation; mutation ... See more keywords
Associations of HER2 Mutation With Immune-Related Features and Immunotherapy Outcomes in Solid Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.799988
Abstract: Background HER2 is one of the most extensively studied oncogenes in solid tumors. However, the association between tumor microenvironment (TME) and HER2 mutation remains elusive, and there are no specific therapies for HER2-mutated tumors. Immune… read more here.
Keywords: immunotherapy outcomes; her2 mutations; solid tumors; mutation ... See more keywords