Articles with "her2 neu" as a keyword



Impact of postoperative radiotherapy and HER2/new overexpression in salivary duct carcinoma

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Published in 2017 at "Strahlentherapie und Onkologie"

DOI: 10.1007/s00066-017-1196-8

Abstract: AimRetrospective Investigation of the prognostic relevance of clinicopathologic parameters in patients with salivary duct carcinoma (SDC).MethodsAn experienced pathologist reviewed 67 patients with de novo SDC or SDC ex pleomorphic adenoma. Paraffin-embedded tumor samples were examined by… read more here.

Keywords: her2 neu; dmfs; sdc; radiotherapy ... See more keywords

Histopathological Study of Gastric Adenocarcinoma with Special Reference to Expression of HER2/neu and Ki-67 Assessed by Immunohistochemistry

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Published in 2024 at "Indian Journal of Medical and Paediatric Oncology"

DOI: 10.1055/s-0044-1788308

Abstract: Abstract Introduction  Gastric cancer has become the third leading cause of cancer deaths globally. It accounts for 5.7% of cancer around the world, with a rate of mortality around 8.2%. Evaluation of human epidermal growth… read more here.

Keywords: cancer; gastric adenocarcinoma; expression; index ... See more keywords

212Pb-conjugated anti-rat HER2/neu antibody against a neu-N derived murine mammary carcinoma cell line: cell kill and RBE in vitro.

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Published in 2022 at "International journal of radiation biology"

DOI: 10.1080/09553002.2022.2033341

Abstract: Purpose In the current work, the RBE of a 212Pb conjugated anti-HER2/neu antibody construct has been evaluated, in vitro, by colony formation assay. The RBE was estimated by comparing two absorbed dose-survival curves: the first… read more here.

Keywords: neu antibody; her2 neu; antibody; 212pb conjugated ... See more keywords

Development 68Ga trastuzumab Fab and bioevaluation by PET imaging in HER2/neu expressing breast cancer patients

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Published in 2022 at "Nuclear Medicine Communications"

DOI: 10.1097/mnm.0000000000001521

Abstract: Supplemental Digital Content is available in the text. Introduction Receptors on breast cancer cells play a crucial role in the management of patients. Trastuzumab is a widely used drug for the treatment of HER2/neu expressing… read more here.

Keywords: fab nota; trastuzumab fab; fab; breast cancer ... See more keywords

Abstract 114: Identification of the actionable target, LILRB4, through genetic linkage analysis of Diversity Outbred (DO) F1 mice expressing HER2(neu)

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-114

Abstract: Our goal is to identify, in situ, the regulatory genes that dictate the onset age and growth rate of spontaneously arising tumors to implement new intervention strategies. For genetic linkage analysis, we crossed HER2(neu) Tg… read more here.

Keywords: cancer; genetic linkage; linkage analysis; tumor ... See more keywords

A phase Ib study of IMU-131 HER2/neu peptide vaccine plus chemotherapy in patients with HER2/neu overexpressing metastatic or advanced adenocarcinoma of the stomach or gastroesophageal junction.

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Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.15_suppl.4030

Abstract: 4030 Background: Gastric cancer is the 5th most common cancer and the 3rd leading cause of cancer deaths. HER2/neu is overexpressed in 15% - 25% of patients with gastric cancer. Monoclonal antibodies against HER2/neu are… read more here.

Keywords: her2 neu; patients her2; imu 131; cancer ... See more keywords

Pathological complete response rate to anthracycline versus non−anthracycline based chemotherapy regimens in localized and regional HER2 neu positive breast cancer.

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Published in 2024 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2024.42.16_suppl.e12632

Abstract: e12632 Background: Debate over the need of anthracycline as part of neoadjuvant chemotherapy in HER2-neu early breast cancer was addressed in many trials with results favoring similar outcomes with or without anthracycline. This was not… read more here.

Keywords: chemotherapy; breast cancer; anthracycline; her2 neu ... See more keywords

Conjugated nanoliposome with the HER2/neu-derived peptide GP2 as an effective vaccine against breast cancer in mice xenograft model

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0185099

Abstract: One of the challenging issues in vaccine development is peptide and adjuvant delivery into target cells. In this study, we developed a vaccine and therapeutic delivery system to increase cytotoxic T lymphocyte (CTL) response against… read more here.

Keywords: dope; her2 neu; gp2; dope mpl ... See more keywords

Evaluation of HER2/neu Expression in Metastatic Axillary Lymph Node Tissue of Breast Cancer Patients Using [99mTc]Tc-(HE)3-G3

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Published in 2024 at "Acta Naturae"

DOI: 10.32607/actanaturae.27448

Abstract: Anatomic visualization and molecular typing of metastatic regional lymph nodes in breast cancer patients are a serious clinical challenge in modern oncology. According to the results of previous studies, [99mTc]Tc-(HE)3-G3 has proven to be a… read more here.

Keywords: her2 neu; breast cancer; cancer patients;

Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.871390

Abstract: The diversity of autologous cells being used and investigated for cancer therapy continues to increase. Mast cells (MCs) are tissue cells that contain a unique set of anti-cancer mediators and are found in and around… read more here.

Keywords: tumor cells; mcs; mast cells; tumor ... See more keywords

Factors Influencing Lymph Node Positivity in HER2/neu+ Breast Cancer Patients

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Published in 2023 at "Current Oncology"

DOI: 10.3390/curroncol30030215

Abstract: Axillary lymph node metastases are a key prognostic factor in breast cancer treatment. Our aim was to evaluate how tumor size, tumor location, and imaging results correlate to axillary lymph node diseases for patients with… read more here.

Keywords: breast cancer; breast; neu breast; her2 neu ... See more keywords