Evaluating the efficacy of immobilized metal affinity chromatography (IMAC) for host cell protein (HCP) removal from anti-HER2 scFv expressed in Escherichia coli.
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DOI: 10.1016/j.pep.2021.106004
Abstract: Host cell proteins (HCPs) are process-related impurities that have influence on product safety and efficacy. HCPs should effectively be removed by chromatographic steps in downstream purification process. In this study, we aimed to evaluate the… read more here.
Keywords: anti her2; purification; concentration; her2 scfv ... See more keywords