Histopathological features of HER2 overexpression in uterine carcinosarcoma: proposal for requirements in HER2 testing for targeted therapy
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DOI: 10.1007/s00428-021-03017-5
Abstract: Uterine carcinosarcoma (UCS) is an uncommon and highly aggressive tumor. There is no HER2 testing protocol for UCS despite the development of HER2 antibody conjugates. We aimed to elucidate histopathological HER2 expression details in UCS,… read more here.
Keywords: her2 testing; features her2; uterine carcinosarcoma; histopathological features ... See more keywords
HER2 testing in gastric cancer: results of a German expert meeting
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DOI: 10.1007/s00432-017-2374-x
Abstract: Valid HER2 testing is essential for optimal therapy of patients with HER2-positive gastric cancer and the correct use of first-line chemotherapy. While testing for HER2 status in breast cancer is routinely performed, this is not… read more here.
Keywords: her2 testing; gastric cancer; testing gastric; german expert ... See more keywords
Impact of repeat HER2 testing after initial equivocal HER2 FISH results using 2013 ASCO/CAP guidelines
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DOI: 10.1007/s10549-017-4479-y
Abstract: PurposeThe updated 2013 American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 (HER2) testing have made some major changes in HER2 fluorescence in situ hybridization (FISH) interpretation… read more here.
Keywords: repeat her2; her2 testing; equivocal cases; her2 fish ... See more keywords
HER2 Testing and Reporting in Endometrial Serous Carcinoma: Practical Recommendations for HER2 Immunohistochemistry and Fluorescent In Situ Hybridization: Proceedings of the ISGyP Companion Society Session at the 2020 USCAP Annual Meeting.
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000711
Abstract: Anti-HER2 therapy has recently emerged as an effective targeted treatment approach for patients with advanced stage and recurrent endometrial serous carcinoma, resulting in significantly prolonged progression-free and overall survival when combined with the standard chemotherapy… read more here.
Keywords: her2 testing; serous carcinoma; pathology; carcinoma ... See more keywords
UK recommendations for HER2 assessment in breast cancer: an update
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DOI: 10.1136/jcp-2022-208632
Abstract: The last UK breast cancer (BC) human epidermal growth factor receptor 2 (HER2) testing guideline recommendations were published in 2015. Since then, new data and therapeutic strategies have emerged. The American Society of Clinical Oncology… read more here.
Keywords: her2 testing; score her2; ihc score; her2 ... See more keywords
HER2 testing: Insights from pathologists’ perspective on challenging HER2 cases.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e12512
Abstract: e12512 Background: HER2 status dictates treatment decisions in breast cancer making the precision and accuracy of laboratory testing essential. While most HER2 testing is straightforward using ASCO-CAP interpretation guidelines, 5% of cases fall into the… read more here.
Keywords: her2 testing; challenging her2; her2 cases; her2 ... See more keywords
Disparities in HER2 testing in breast cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e13084
Abstract: e13084 Background: Although targeted therapies directed at human epidermal growth factor-2 (HER2) impact breast cancer outcomes, studies have found geographic variation in testing rates. We report population-based patterns of HER2 testing by patient, tumor and… read more here.
Keywords: breast cancer; her2 testing; test done;