Preoperative Differentiation of HER2‐Zero and HER2‐Low from HER2‐Positive Invasive Ductal Breast Cancers Using BI‐RADS MRI Features and Machine Learning Modeling
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.29447
Abstract: Accurate determination of human epidermal growth factor receptor 2 (HER2) is important for choosing optimal HER2 targeting treatment strategies. HER2‐low is currently considered HER2‐negative, but patients may be eligible to receive new anti‐HER2 drug conjugates. read more here.
Keywords: zero her2; her2 low; her2; differentiation her2 ... See more keywords
The impact of HER2-low status on pathological complete response and disease-free survival in early-stage breast cancer
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DOI: 10.1186/s12885-024-13064-1
Abstract: The HER-2 status of breast cancer (BC) has been classified as negative or positive for a long time. Given the efficacy of novel anti-HER2-targeted antibody drug conjugates (ADCs) in HER2-low BC, a distinct subgroup of… read more here.
Keywords: cancer; her2 low; low status; impact ... See more keywords
Differences in Sentinel lymph node biopsy outcomes and prognosis between HER2-low and HER2-zero breast cancer
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DOI: 10.1186/s12885-025-14970-8
Abstract: Human epidermal growth factor receptor 2 (HER2)-low breast cancer has been recognized as a distinct biological subset within HER2-negative breast cancer. This study aimed to examine the differences in sentinel lymph node metastasis (SLNM) rates… read more here.
Keywords: breast cancer; breast; her2 low; her2 ... See more keywords
Comparative analysis of metabolic characteristics and prognostic stratification of HER2-low and HER2-zero breast cancer using 18F-FDG PET/CT imaging
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DOI: 10.1186/s40644-024-00812-6
Abstract: Recent advancements in novel anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugates (ADCs) have highlighted the emerging HER2-low breast cancer subtype with promising therapeutic efficacy. This study aimed to comparatively analyze the metabolic characteristics… read more here.
Keywords: her2 zero; her2; her2 low; breast cancer ... See more keywords
Pathological complete response and prognosis after neoadjuvant chemotherapy in patients with HER2-low breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of diagnostic pathology"
DOI: 10.2139/ssrn.4333242
Abstract: BACKGROUND The development of novel human epidermal growth factor receptor 2 (HER2) antibody drug conjugates brings encouraging opportunities for the treatment of HER2-low breast cancer. In this study, we investigated the clinical factors and prognosis… read more here.
Keywords: low breast; her2 zero; her2; breast cancer ... See more keywords
Analysis of factors influencing the efficacy of NAC and prognosis between HER2-zero and HER2-low HR negative breast cancer
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DOI: 10.3389/fcell.2024.1417271
Abstract: Objective: The aim of this paper was to assess the differences in clinicopathological characteristics, efficacy and prognosis of neoadjuvant chemotherapy (NAC) in human epidermal growth factor receptor2(HER2)-zero and HER2-low hormone receptor (HR)-negative breast cancer (BC)… read more here.
Keywords: cancer; zero her2; her2 low; prognosis ... See more keywords
Clinicopathological Characteristics and Prognosis of HER2-Low Early-Stage Breast Cancer: A Single-Institution Experience
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DOI: 10.3389/fonc.2022.906011
Abstract: Background Human epidermal growth factor 2 (HER2)-low breast cancer, which is defined as HER2 1+ or 2+ in immunohistochemistry without gene amplification, accounts for a considerable part of all breast cancers. However, it remains controversial… read more here.
Keywords: breast cancer; her2 low; her2; her2 zero ... See more keywords
Preliminary study on DCE-MRI radiomics analysis for differentiation of HER2-low and HER2-zero breast cancer
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DOI: 10.3389/fonc.2024.1385352
Abstract: Purpose This study aims to evaluate the utility of radiomic features from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in distinguishing HER2-low from HER2-zero breast cancer. Patients and methods We retrospectively analyzed 118 MRI cases, including… read more here.
Keywords: low her2; her2 low; her2; dce mri ... See more keywords