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Lapatinib with ECF/X in the first-line treatment of metastatic gastric cancer according to HER2neu and EGFR status: a randomized placebo-controlled phase II study (EORTC 40071)

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Published in 2018 at "Cancer Chemotherapy and Pharmacology"

DOI: 10.1007/s00280-018-3667-8

Abstract: PurposeHER2-targeted therapy with trastuzumab and (CF/X) prolonged overall survival (OS) in metastatic HER2neu+ gastric carcinoma (GC). Lapatinib inhibits both EGFR and HER2neu. We investigated the efficacy and safety of lapatinib with epirubicin (E) + CF/X in GC… read more here.

Keywords: status; her2neu; her2neu egfr; according her2neu ... See more keywords