Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6585
Abstract: About 70% of the world population is currently using medicinal herbs as complementary or alternative medicine, which is increasing at a tremendous pace in both developed and developing countries in the last two decades (World… read more here.
Keywords: treatment; herbs; treatment cardiovascular; herb drug ... See more keywords
Herb-drug interaction: The effect of Polygonum capitatum extract on pharmacokinetics of levofloxacin in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113832
Abstract: Polygonum capitatum is a traditional medicinal plant of the Miao people and has been used to treat a variety of urological disorders in China for many years. Preparations made from water-soluble P. capitatum extracts, Relinqing®… read more here.
Keywords: polygonum capitatum; drug; capitatum extract; capitatum ... See more keywords
Evaluation of the Herb-Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07912
Abstract: Ginger is currently one of the most popular herbs commonly added to diverse foods, beverages, and dietary supplements. We evaluated the ability of a well-characterized ginger extract, and several of its phytoconstituents, to activate select… read more here.
Keywords: interaction hdi; herb drug; ginger extract; drug interaction ... See more keywords
Network Analysis of the Herb–Drug Interactions of Citrus Herbs Inspired by the “Grapefruit Juice Effect”
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04579
Abstract: This study was performed to investigate the herb–drug interactions (HDIs) of citrus herbs (CHs), which was inspired by the “grapefruit (GF) juice effect”. Based on network analysis, a total of 249 components in GF and… read more here.
Keywords: citrus herbs; effect; drug interactions; herb drug ... See more keywords
Herb-drug interactions: a mechanistic approach.
Sign Up to like & getrecommendations! Published in 2020 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2020.1738454
Abstract: In India, traditional herbal medicines have been an essential part of therapy for the last centuries. However, a large portion of the general populace is using these therapies in combination with allopathy lacking a proper… read more here.
Keywords: literature; drug interactions; interactions mechanistic; drug ... See more keywords
Evaluation of herb-drug interaction of ambrisentan with shikonin based on UPLC-MS/MS
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2021.1964544
Abstract: Abstract Context Ambrisentan is an oral endothelin-receptor antagonist (ERA). However, there is no report on the interaction between ambrisentan and shikonin. Objective To investigate the effect of shikonin on ambrisentan metabolism in vivo and in… read more here.
Keywords: drug interaction; shikonin; ambrisentan shikonin; interaction ... See more keywords
Assessment of Herb-Drug Interaction Potential of Five Common Species of Licorice and Their Phytochemical Constituents.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dietary supplements"
DOI: 10.1080/19390211.2022.2050875
Abstract: Abstract The dried roots and rhizomes of Glycyrrhiza species (G. glabra, G. uralensis and G. inflata), commonly known as licorice, have long been used in traditional medicine. In addition, two other species, G. echinata and… read more here.
Keywords: interaction potential; activity; herb drug; drug interaction ... See more keywords
Pharmacokinetics and Pharmacodynamic Herb-Drug Interaction of Piperine with Atorvastatin in Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmaa126
Abstract: Herbals that are widely consumed as therapeutic alternatives to conventional drugs for cardiovascular diseases, may lead to herb-drug interactions (HDIs). Atorvastatin (ATR) is drug of choice for hyperlipidemia and is extensively metabolized through CYP3A4 enzyme.… read more here.
Keywords: administration; drug; pharmacokinetics pharmacodynamic; pip ... See more keywords
Rhinacanthin-C Mediated Herb-Drug Interactions with Drug Transporters and Phase I Drug-Metabolizing Enzymes
Sign Up to like & getrecommendations! Published in 2019 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.118.085647
Abstract: Rhinacanthin-C is a major active constituent in Rhinacanthus nasutus (L.) Kurz, a plant widely used in herbal remedies. Its potential for pharmacokinetic herb-drug interaction may exist with drug transporters and drug metabolizing enzymes. This study… read more here.
Keywords: drug metabolizing; drug interaction; drug; ic50 ... See more keywords
Comparison of eight screening tools to detect interactions between herbal supplements and oncology agents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155220905009
Abstract: Introduction Patients with cancer are increasingly using herbal supplements, unaware that supplements can interact with oncology treatment. Herb–drug interaction management is critical to ensure optimal treatment outcomes. Several screening tools exist to detect drug–drug interactions,… read more here.
Keywords: drug interaction; drug; performance; herb drug ... See more keywords
Patient needs and preferences for herb-drug-disease interaction alerts: a structured interview study
Sign Up to like & getrecommendations! Published in 2017 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-017-1630-6
Abstract: BackgroundWhile complementary and alternative medicine (CAM) is commonly used in the United States and elsewhere, and hazardous interactions with prescription drugs can occur, patients do not regularly communicate with physicians about their CAM use. The… read more here.
Keywords: herb drug; medicine; preferences herb; drug disease ... See more keywords