Articles with "herb drug" as a keyword



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Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies

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Published in 2020 at "Phytotherapy Research"

DOI: 10.1002/ptr.6585

Abstract: About 70% of the world population is currently using medicinal herbs as complementary or alternative medicine, which is increasing at a tremendous pace in both developed and developing countries in the last two decades (World… read more here.

Keywords: treatment; herbs; treatment cardiovascular; herb drug ... See more keywords

Herb-drug interaction: The effect of Polygonum capitatum extract on pharmacokinetics of levofloxacin in rats.

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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2020.113832

Abstract: Polygonum capitatum is a traditional medicinal plant of the Miao people and has been used to treat a variety of urological disorders in China for many years. Preparations made from water-soluble P. capitatum extracts, Relinqing®… read more here.

Keywords: polygonum capitatum; drug; capitatum extract; capitatum ... See more keywords

Evaluation of the Herb-Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents.

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Published in 2023 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c07912

Abstract: Ginger is currently one of the most popular herbs commonly added to diverse foods, beverages, and dietary supplements. We evaluated the ability of a well-characterized ginger extract, and several of its phytoconstituents, to activate select… read more here.

Keywords: interaction hdi; herb drug; ginger extract; drug interaction ... See more keywords

Network Analysis of the Herb–Drug Interactions of Citrus Herbs Inspired by the “Grapefruit Juice Effect”

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c04579

Abstract: This study was performed to investigate the herb–drug interactions (HDIs) of citrus herbs (CHs), which was inspired by the “grapefruit (GF) juice effect”. Based on network analysis, a total of 249 components in GF and… read more here.

Keywords: citrus herbs; effect; drug interactions; herb drug ... See more keywords

Herb-drug interactions: a mechanistic approach.

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Published in 2020 at "Drug and chemical toxicology"

DOI: 10.1080/01480545.2020.1738454

Abstract: In India, traditional herbal medicines have been an essential part of therapy for the last centuries. However, a large portion of the general populace is using these therapies in combination with allopathy lacking a proper… read more here.

Keywords: literature; drug interactions; interactions mechanistic; drug ... See more keywords

Herb-drug interaction potential of Astragali Radix: a metabolic perspective

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Published in 2024 at "Drug Metabolism Reviews"

DOI: 10.1080/03602532.2024.2441235

Abstract: Abstract Astragali Radix (AR) is one of the most widely used herbs in Asia and has a wide range of biological activities. These activities are attributed to its various compounds like flavonoids, saponins, and polysaccharides.… read more here.

Keywords: drug; astragali radix; herb drug; drug interaction ... See more keywords

Evaluation of herb-drug interaction of ambrisentan with shikonin based on UPLC-MS/MS

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Published in 2021 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2021.1964544

Abstract: Abstract Context Ambrisentan is an oral endothelin-receptor antagonist (ERA). However, there is no report on the interaction between ambrisentan and shikonin. Objective To investigate the effect of shikonin on ambrisentan metabolism in vivo and in… read more here.

Keywords: drug interaction; shikonin; ambrisentan shikonin; interaction ... See more keywords

Assessment of Herb-Drug Interaction Potential of Five Common Species of Licorice and Their Phytochemical Constituents.

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Published in 2022 at "Journal of dietary supplements"

DOI: 10.1080/19390211.2022.2050875

Abstract: Abstract The dried roots and rhizomes of Glycyrrhiza species (G. glabra, G. uralensis and G. inflata), commonly known as licorice, have long been used in traditional medicine. In addition, two other species, G. echinata and… read more here.

Keywords: interaction potential; activity; herb drug; drug interaction ... See more keywords

Clinically Relevant Herb–Drug Interactions: A 30-Year Historical Assessment

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Published in 2024 at "Journal of Dietary Supplements"

DOI: 10.1080/19390211.2024.2327544

Abstract: Abstract The Dietary Supplement Health and Education Act, a legislative measure ushering in a novel class of complementary healthcare products known as dietary supplements, will mark its 30th anniversary in October 2024. Over this 30-year… read more here.

Keywords: clinically relevant; year; drug interactions; drug ... See more keywords

Pharmacokinetics and Pharmacodynamic Herb-Drug Interaction of Piperine with Atorvastatin in Rats.

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Published in 2021 at "Journal of chromatographic science"

DOI: 10.1093/chromsci/bmaa126

Abstract: Herbals that are widely consumed as therapeutic alternatives to conventional drugs for cardiovascular diseases, may lead to herb-drug interactions (HDIs). Atorvastatin (ATR) is drug of choice for hyperlipidemia and is extensively metabolized through CYP3A4 enzyme.… read more here.

Keywords: administration; drug; pharmacokinetics pharmacodynamic; pip ... See more keywords

Rhinacanthin-C Mediated Herb-Drug Interactions with Drug Transporters and Phase I Drug-Metabolizing Enzymes

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Published in 2019 at "Drug Metabolism and Disposition"

DOI: 10.1124/dmd.118.085647

Abstract: Rhinacanthin-C is a major active constituent in Rhinacanthus nasutus (L.) Kurz, a plant widely used in herbal remedies. Its potential for pharmacokinetic herb-drug interaction may exist with drug transporters and drug metabolizing enzymes. This study… read more here.

Keywords: drug metabolizing; drug interaction; drug; ic50 ... See more keywords