Herbal compounds for rheumatoid arthritis: Literatures review and cheminformatics prediction
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6509
Abstract: Rheumatoid arthritis (RA) is a systemic disease characterized by autoimmunity, joint inflammation, and cartilage destruction, which affects 0.5–1% of the population. Many compounds from herbal medicines show the potentials to treat RA. On this basis,… read more here.
Keywords: drug likeness; likeness properties; rheumatoid arthritis; herbal compounds ... See more keywords
Protective effects of herbal compounds against cyclophosphamide-induced organ toxicity: a pathway-centered approach
Sign Up to like & getrecommendations! Published in 2025 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2025.2455442
Abstract: Abstract Cyclophosphamide is a key component of numerous chemotherapeutic protocols, demonstrating broad-spectrum efficacy against various malignancies and non-cancerous conditions. This review examines CPM’s metabolic pathways, therapeutic applications, and its resulting organ-specific toxicities. Despite its clinical… read more here.
Keywords: protective effects; cyclophosphamide induced; compounds cyclophosphamide; toxicity ... See more keywords
Traditional herbal compounds as candidates to inhibit the SARS-CoV-2 main protease: an in silico study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2021.2023646
Abstract: Abstract COVID-19, a disease caused by the SARS-CoV-2 virus, is responsible for a pandemic since March 2020 and it has no cure. Therefore, herein, different theoretical methods were used to obtain potential candidates from herbal… read more here.
Keywords: cov main; main protease; candidates inhibit; herbal compounds ... See more keywords
Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Immunology Research"
DOI: 10.1155/2018/9348046
Abstract: Since microglia possess both neuroprotective and neurotoxic potential, they play a crucial role in the central nervous system (CNS). Excessive microglial activation induces inflammation-mediated neuronal damage and degeneration. At present, numerous herbal compounds are able… read more here.
Keywords: herbal compounds; role; activation; compounds play ... See more keywords
A systematic review of effectiveness and safety of some herbal compounds as treatment for primary insomnia
Sign Up to like & getrecommendations! Published in 2024 at "European Psychiatry"
DOI: 10.1192/j.eurpsy.2024.1608
Abstract: Introduction Sleep related disorders affect around 30% of people all over the world, and evidence shows that 10% require therapeutic intervention. Insomnia represents the most common disturbance of sleep, defined as the experience of poor… read more here.
Keywords: quality; insomnia; primary insomnia; herbal compounds ... See more keywords
Computational Screening of IL-1 and IL-6 Inhibitors for Rheumatoid Arthritis: Insights from Molecular Docking and Dynamics Analysis.
Sign Up to like & getrecommendations! Published in 2025 at "Current pharmaceutical design"
DOI: 10.2174/0113816128344776250222043907
Abstract: BACKGROUND Rheumatoid arthritis (RA) remains a significant therapeutic challenge due to its chronic inflammatory nature. Consequently, many patients turn to alternative therapies, such as herbal compounds and supplements, when conventional treatments prove relatively ineffective or… read more here.
Keywords: molecular docking; analysis; rheumatoid arthritis; herbal compounds ... See more keywords
Molecular Aspects and Therapeutic Implications of Herbal Compounds Targeting Different Types of Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28020750
Abstract: Due to genetic changes in DNA (deoxyribonucleic acid) sequences, cancer continues to be the second most prevalent cause of death. The traditional target-directed approach, which is confronted with the importance of target function in healthy… read more here.
Keywords: molecular aspects; herbal compounds; implications herbal; aspects therapeutic ... See more keywords
Molecular docking and simulation analysis of selected herbal compounds against GP63, FPPS, and NMT, three important Leishmania major proteins
Sign Up to like & getrecommendations! Published in 2025 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/rps.rps_123_24
Abstract: Background and purpose: Leishmaniasis has been categorized as one of the most significant tropical illnesses, often ignored. This study aimed to find effective plant compounds to combat the pathogenicity of the Leishmania parasite. Experimental approach:… read more here.
Keywords: molecular docking; docking simulation; leishmania; simulation ... See more keywords