Population screening to identify women at risk for hereditary breast cancer syndromes: The path forward or the road not taken?
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DOI: 10.1002/cncr.33867
Abstract: INTRODUCTION Despite 2 decades of research demonstrating the clinical benefit of genetic counseling and germline genetic testing for the hereditary breast and ovarian cancer (HBOC) syndrome and the publication of evidencebased guidelines recommending family history… read more here.
Keywords: cancer; genetic counseling; hereditary breast; risk ... See more keywords
Process evaluation of a culturally targeted video for Latinas at risk of hereditary breast and ovarian cancer
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DOI: 10.1002/jgc4.1361
Abstract: This paper presents a process evaluation of a culturally targeted narrative video about hereditary breast and ovarian cancer (HBOC) for Latina women at risk for HBOC. Spanish‐speaking Latina women at risk for HBOC participated in… read more here.
Keywords: evaluation culturally; video; risk; process evaluation ... See more keywords
Challenges and opportunities in the establishment of a hereditary breast cancer clinic at an academic medical center in a low‐middle income country
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DOI: 10.1002/jgc4.1555
Abstract: It is now standard of care to offer genetic testing to patients at risk of hereditary breast cancer and make management decisions based on these results. Although great strides have been made in ensuring access… read more here.
Keywords: breast; genetic testing; hereditary breast; breast cancer ... See more keywords
Multigene panel testing for hereditary breast and ovarian cancer in the province of Ontario
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DOI: 10.1007/s00432-020-03377-6
Abstract: Purpose The aim of this study was to determine the diagnostic yield of multigene panel testing among patients referred with hereditary breast and ovarian cancer (HBOC). Methods Patients who met provincial eligibility criteria were tested… read more here.
Keywords: multigene panel; breast ovarian; panel testing; cancer ... See more keywords
Hereditary breast cancer and fertility preservation outcomes
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DOI: 10.1007/s10815-022-02486-0
Abstract: To determine the frequency of hereditary breast cancer associated with different mutated genes and to evaluate fertility preservation (FP) outcomes among young women with hereditary breast cancer when compared to non-hereditary breast cancer. A retrospective… read more here.
Keywords: breast cancer; fertility preservation; hereditary breast; cancer ... See more keywords
Comparison of clinical features and oncologic outcomes between familial (non-hereditary) and hereditary breast cancer in Korean female patients.
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DOI: 10.1016/j.asjsur.2019.12.001
Abstract: BACKGROUND The authors compared the clinical features between familial (non-hereditary) and hereditary breast cancer. And we also analyzed their oncologic outcomes to establish appropriate surveillance protocol for familial (non-hereditary) and hereditary breast cancer. METHODS Among… read more here.
Keywords: non hereditary; breast cancer; cancer; familial non ... See more keywords
Overview of hereditary breast and ovarian cancer (HBOC) guidelines across Europe.
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DOI: 10.1016/j.ejmg.2021.104350
Abstract: Hereditary breast and ovarian cancer (HBOC) is a syndrome defined by an increased risk of developing breast and/or ovarian cancer most commonly due to germline disease-causing variants in the BRCA1 and BRCA2 genes, but also… read more here.
Keywords: risk; breast; breast ovarian; ovarian cancer ... See more keywords
Hereditary Breast and Hereditary Ovarian Cancer: Implications for the Oncology Nurse.
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DOI: 10.1016/j.soncn.2018.12.001
Abstract: OBJECTIVES To review heredity cancer syndromes involving the breasts, ovaries, or breast and ovaries. To recommend useful professional and patient resources on cancer genetics. A case study of germline BRCA genetic testing after allogeneic bone… read more here.
Keywords: genetics; hereditary ovarian; breast hereditary; cancer ... See more keywords
The budgetary impact of genetic testing for hereditary breast cancer for the statutory health insurance
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DOI: 10.1080/03007995.2019.1654689
Abstract: Abstract Objectives: Potential opportunities and challenges of predictive genetic risk classification of healthy persons are currently discussed. However, the budgetary impact of rising demand is uncertain. This project aims to evaluate budgetary consequences of predictive… read more here.
Keywords: statutory health; health insurance; cancer; health ... See more keywords
Determining the accuracy of next generation sequencing based copy number variation analysis in Hereditary Breast and Ovarian Cancer
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DOI: 10.1080/14737159.2022.2048373
Abstract: ABSTRACT Background Copy number variations (CNVs) are commonly associated with malignancies, including hereditary breast and ovarian cancers. Next generation sequencing (NGS) provides solutions for CNV detection in a single run. This study aimed to compare… read more here.
Keywords: ngs cnv; breast ovarian; analysis; next generation ... See more keywords
Reducing Disparities in Receipt of Genetic Counseling for Underserved Women at Risk of Hereditary Breast and Ovarian Cancer.
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DOI: 10.1089/jwh.2019.7984
Abstract: Purpose: Genetic counseling (GC) provides critical risk prediction information to women at-risk of carrying a genetic alternation; yet racial/ethnic and socioeconomic disparities persist with regard to GC uptake. This study examined patterns of GC uptake… read more here.
Keywords: genetic counseling; women risk; breast ovarian; ovarian cancer ... See more keywords