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Published in 2025 at "International journal of clinical oncology"
DOI: 10.1007/s10147-025-02892-1
Abstract: Approximately 5% of all colorectal cancers have a strong genetic component and are classified as hereditary colorectal cancer (HCRC). Some of the unique features commonly seen in HCRC cases include early age of onset, synchronous/metachronous…
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Keywords:
colorectal cancer;
cancer;
hereditary colorectal;
hcrc ... See more keywords
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Published in 2018 at "Journal of Community Genetics"
DOI: 10.1007/s12687-018-0385-1
Abstract: Overlapping phenotypes between different hereditary colorectal cancer (CRC) syndromes together with a growing demand for cancer genetic testing and improved sequencing technology call for adjusted patient selection and adapted diagnostic routines. Here we present a…
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Keywords:
hereditary colorectal;
colorectal cancer;
retrospective evaluation;
cancer ... See more keywords
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Published in 2024 at "Annals of The Royal College of Surgeons of England"
DOI: 10.1308/rcsann.2024.0024
Abstract: Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Over the past three decades, extensive efforts have sought to elucidate the genomic landscape of CRC. These studies reveal that CRC is highly heterogeneous…
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Keywords:
colorectal cancer;
cancer;
sporadic hereditary;
crc ... See more keywords
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Published in 2025 at "Diagnostics"
DOI: 10.3390/diagnostics15070819
Abstract: Background: Hereditary colorectal cancer syndromes, including familial adenomatous polyposis (FAP), Lynch syndrome (LS), and Peutz–Jeghers syndrome (PJS), are associated with an increased risk of small bowel cancer (SBC). Due to the low incidence and non-specific…
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Keywords:
cancer;
small bowel;
hereditary colorectal;
risk ... See more keywords