Stagnation in quality of next-generation sequencing assays for the diagnosis of hereditary hematopoietic malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of genetic counseling"
DOI: 10.1101/2022.06.14.22276069
Abstract: Importance: Hereditary hematopoietic malignancies (HHMs) are hereditary cancer syndromes that constitute at least 14% of all myeloid malignancies, but genetic assays used to diagnose HHMs have historically been of variable quality. Here, we demonstrate that… read more here.
Keywords: quality; hhm; diagnosis; hematopoietic malignancies ... See more keywords
Clinical considerations at the intersection of hematopoietic cell transplantation and hereditary hematopoietic malignancy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1180439
Abstract: In recent years, advances in genetics and the integration of clinical-grade next-generation sequencing (NGS) assays into patient care have facilitated broader recognition of hereditary hematopoietic malignancy (HHM) among clinicians, in addition to the identification and… read more here.
Keywords: clinical considerations; hematopoietic malignancy; considerations intersection; transplantation ... See more keywords