hERG1 and HIF-2α Behave as Biomarkers of Positive Response to Bevacizumab in Metastatic Colorectal Cancer Patients☆
Sign Up to like & getrecommendations! Published in 2020 at "Translational Oncology"
DOI: 10.1016/j.tranon.2020.01.001
Abstract: Background: In search of novel biomarkers of response to bevacizumab in metastatic colorectal cancer (mCRC), we analyzed the expression and prognostic role of several proteins related to angiogenesis. Methods: A retrospective, multicenter study on 80… read more here.
Keywords: hif; bevacizumab; response bevacizumab; bevacizumab metastatic ... See more keywords
hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer
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DOI: 10.1186/s12935-018-0592-1
Abstract: BackgroundBreast cancer (BC) is the most frequent malignancy among females worldwide. Despite several efforts and improvements in early diagnosis and treatment, there are still tumors characterized by an aggressive behavior due to unfavorable biology, thus… read more here.
Keywords: expression associates; herg1 expression; expression; herg1 ... See more keywords
Prognostic role of hERG1 Potassium Channels in Neuroendocrine Tumours of the Ileum and Pancreas
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DOI: 10.3390/ijms231810623
Abstract: hERG1 potassium channels are widely expressed in human cancers of different origins, where they affect several key aspects of cellular behaviour. The present study was designed to evaluate the expression and clinical relevance of hERG1… read more here.
Keywords: herg1 potassium; herg1; ileum pancreas; potassium channels ... See more keywords